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| Status |
Public on Aug 08, 2018 |
| Title |
Impact of Cugbp1 knockout on skeletal muscle and brain trancsriptome in neonatal mice |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
To elucidate the role of Cugbp1 knockout on the structure and function of skeletal muscle and brain, we have performed a microarray of mRNA obtained from skeletal muscle and brain samples obtained from neonatal WT and Cugbp1 KO mice.
Between-genotype differences were assessed using a Student's T-test, with a p-value cutoff of 0.05 and fold change cutoff of 1.5. 929 genes were identified as differentially regulated; ontological enrichments within this geneset indicated Cugbp1 may regulate differentiation, extracellulat matrix and other muscle functions during myogenesis.
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| Overall design |
The impact of Cugbp1 knockout on the skeletal muscle and brain transcriptome was assessed through a microarray of mRNA obtained from skeletal muscle and brain samples in WT and Cugbp1 KO neonatal mice.
The submitter states that raw data are not available for this series.
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| Contributor(s) |
Timchenko L, Karns R |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Aug 09, 2016 |
| Last update date |
Aug 08, 2018 |
| Contact name |
Rebekah Karns |
| E-mail(s) |
Rebekah.Karns@cchmc.org
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| Organization name |
Cincinnati Children's Hospital Medical Center
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| Department |
Gastroenterology, Hepatology, & Nutrition
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| Street address |
3333 Burnet Ave
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| City |
Cincinnati |
| State/province |
OH |
| ZIP/Postal code |
45276 |
| Country |
USA |
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| Platforms (1) |
| GPL10787 |
Agilent-028005 SurePrint G3 Mouse GE 8x60K Microarray (Probe Name version) |
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| Samples (14)
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| Relations |
| BioProject |
PRJNA338321 |
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