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Series GSE8564 Query DataSets for GSE8564
Status Public on Jul 22, 2008
Title Analysis of Aire effects on individual mice of different genetic backgrounds
Organism Mus musculus
Experiment type Expression profiling by array
Summary We compared gene expression profiles of aire-deficient and wild-type littermate thymic medullary epithelial cells. This was done in order to determine whether Aire's effects differed among strains, and also among individuals of the same strain.
Keywords: genetic modification
Overall design Individual thymi were digested with collagenase, dispase and DNAse, and meduallary epithelial cells with the phenotype CD45-G8.8+Ly51intMHCclasssIIhi were isolated by FACS.
Contributor(s) Venanzi ES, Benoist C, Mathis D
Citation(s) 18838677
Submission date Jul 23, 2007
Last update date Feb 11, 2019
Contact name CBDM Lab
Phone 617-432-7747
Organization name Harvard Medical School
Department Microbiology and Immunobiology
Street address 77 Avenue Louis Pasteur
City Boston
State/province MA
ZIP/Postal code 02215
Country USA
Platforms (1)
GPL1261 [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
Samples (20)
GSM212611 classIIhiMECs B6aireWT rep1
GSM212612 classIIhiMECs B6aireWT rep2
GSM212613 classIIhiMECs B6aireWT rep3
BioProject PRJNA101707

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE8564_RAW.tar 73.4 Mb (http)(custom) TAR (of CEL)
Raw data provided as supplementary file
Processed data included within Sample table

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