|
| Status |
Public on Aug 24, 2016 |
| Title |
Mouse Dux is myotoxic and shares partial functional homology with its human paralog DUX4 |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
We report the RNA-seq experiments performed in human myoblasts transfected with human DUX4 and mouse Dux.
|
| |
|
| Overall design |
Comparison of genes up- and down-regulated by DUX4 and Dux in human myoblasts to identify pathways similiarly regulated by both transcription factors.
|
| |
|
| Contributor(s) |
Harper SQ, Eidahl JO, Giesige CR, Domire JS, Wallace LM, Fowler AM, Guckes S, Garwick-Coppens S, Labhart P |
| Citation(s) |
28173143 |
| Submission date |
Aug 23, 2016 |
| Last update date |
May 15, 2019 |
| Contact name |
Scott Q Harper |
| E-mail(s) |
Scott.Harper@nationwidechildrens.org
|
| Phone |
(614) 355-2893
|
| Organization name |
Nationwide Children's Hospital
|
| Department |
Gene Therapy
|
| Lab |
Harper
|
| Street address |
700 Children's Drive
|
| City |
Columbus |
| State/province |
Ohio |
| ZIP/Postal code |
43205 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL20301 |
Illumina HiSeq 4000 (Homo sapiens) |
|
| Samples (9)
|
| GSM2288028 |
Human DUX4 transfected myoblasts [DUX4-1] |
| GSM2288029 |
Human DUX4 transfected myoblasts [DUX4-2] |
| GSM2288030 |
Human DUX4 transfected myoblasts [DUX4-3] |
| GSM2288031 |
Mouse Dux transfected human myoblasts [mDUX-1] |
| GSM2288032 |
Mouse Dux transfected human myoblasts [mDUX-2] |
| GSM2288033 |
Mouse Dux transfected human myoblasts [mDUX-3] |
| GSM2288034 |
pCIneo transfected human myoblasts [pCINeo-1] |
| GSM2288035 |
pCIneo transfected human myoblasts [pCINeo-2] |
| GSM2288036 |
pCIneo transfected human myoblasts [pCINeo-3] |
|
| Relations |
| BioProject |
PRJNA339785 |
| SRA |
SRP082564 |
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