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Series GSE8679 Query DataSets for GSE8679
Status Public on Jan 11, 2008
Title Gene expression in mouse white adipose tissue
Organism Mus musculus
Experiment type Expression profiling by array
Summary Trans-10, Cis-12 conjugated linoleic acid (t10c12 CLA) causes fat loss in mouse white adipose tissue (WAT). The early transcriptome changes in WAT were analyzed using high-density microarrays to better characterize the signaling pathways responding to t10c12 CLA. Their gene expression responses between 4 to 24 hr after treatment showed a common set of early gene expression changes indicative of an integrated stress response (ISR).
Keywords: control/treatment time course
 
Overall design Mouse WAT RNA for each time point was isolated from two control and two treatment samples for analysis on four microarrays. The two control and two treatment samples consisted of RP tissues from 5 pooled mice for each sample, requiring a total of twenty mice for the four samples taken at each time point.
 
Contributor(s) LaRosa C, Riethoven JM, Chen H, Xia Y, Zhou Y, Chen M, Miner J, Fromm ME
Citation(s) 17878318
Submission date Aug 03, 2007
Last update date Feb 11, 2019
Contact name Jean-Jack M. Riethoven
E-mail(s) jeanjack@unl.edu
Organization name University of Nebraska-Lincoln
Department Beadle Center for Biotechnology
Lab Bioinformatics Core Research Facility
Street address 1901 Vine Street
City Lincoln
State/province NE
ZIP/Postal code 68588-0665
Country USA
 
Platforms (1)
GPL1261 [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
Samples (12)
GSM215232 mouse white adipose tissue, CLA fed, T1, biological rep1
GSM215233 mouse white adipose tissue, CLA fed, T1, biological rep2
GSM215234 mouse white adipose tissue, LA fed (control), T1, biological rep1
This SubSeries is part of SuperSeries:
GSE11384 Trans-10, cis-12 conjugated linoleic acid activates the integrated stress response pathway in adipocytes
Relations
BioProject PRJNA109031

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE8679_12h_RosettaResolver_processed_ratio.xls 3.0 Mb (ftp)(http) XLS
GSE8679_24hr_RosettaResolver_processed_ratio.xls 3.0 Mb (ftp)(http) XLS
GSE8679_4hr_RosettaResolver_processed_ratio.xls 3.0 Mb (ftp)(http) XLS
GSE8679_RAW.tar 38.6 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table
Processed data are available on Series record
Raw data provided as supplementary file

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