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Series GSE868 Query DataSets for GSE868
Status Public on May 10, 2004
Title Mouse Kidney - Effect of Low Phosphate Diet in Normal and Hyp Mice
Organism Mus musculus
Experiment type Expression profiling by array
Summary This is a study of the change in gene expression in mouse kidney after feeding control (1.0% P) or low phosphate diet (0.03% P) for 3 or 5 days to normal or Hyp (X-linked hypophosphatemic) mice at 5 weeks of age. The mice were C57BL/6J. Normal wild-type mice, hemizygous Hyp (Hyp/Y) male mice, or heterozygous (Hyp/+) female mice were used. The gene is dominant, so that the two genders are equally affected with low renal retention of phosphate and severity of their bone disease. RNA from 3 mice were pooled for each microarray. The arrays were processed as described in the Affymetrix GeneChip Expression Analysis Technical Manual (copyright 2001, Affymetrix, Inc., Santa Clara, CA), rev. 1, Part number 701021. The data for each array were scaled to an average signal value of 500 for all genes on the array.
Keywords = mouse
Keywords = kidney
Keywords = low phosphate diet
Keywords = Hyp
Keywords = Phex
Keywords = X-linked hypophosphatemia
Keywords: repeat sample
 
 
Contributor(s) Meyer RA, Meyer MH
Citation(s) 15054142
Submission date Dec 10, 2003
Last update date Feb 18, 2018
Contact name Ralph A. Meyer
E-mail(s) ralpham@aol.com
Organization name Carolinas Medical Center
Department Orthopaedic Research Laboratory
Lab Cannon Research Center, Rm. 304
Street address P.O. Box 32861
City Charlotte
State/province NC
ZIP/Postal code 28232-2861
Country USA
 
Platforms (1)
GPL81 [MG_U74Av2] Affymetrix Murine Genome U74A Version 2 Array
Samples (20)
GSM13451 Sample 01 Kidney Normal mouse - Control diet
GSM13452 Sample 02 Kidney Normal Mouse - Low Phosphate Diet
GSM13453 Sample 03 Kidney Hyp Mouse - Control Diet
Relations
BioProject PRJNA87885

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