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Series GSE8681 Query DataSets for GSE8681
Status Public on Jan 11, 2008
Title Gene expression in mouse 3T3-L1 adipocyte tissue culture treated with CLA
Organism Mus musculus
Experiment type Expression profiling by array
Summary Trans-10, Cis-12 conjugated linoleic acid (t10c12 CLA) causes fat loss in mouse 3T3-L1 adipocyte tissue culture. The early transcriptome changes were analyzed using high-density microarrays to better characterize the signaling pathways responding to t10c12 CLA. Their gene expression responses between 4 to 24 hr after treatment showed a common set of early gene expression changes indicative of an integrated stress response (ISR).
Keywords: control/treatment time course
Overall design Mouse 3T3-L1 RNA for each time point was isolated from control and treatment samples for analysis on microarrays with two to four biological reps.
Contributor(s) LaRosa C, Riethoven JM, Chen H, Xia Y, Zhou Y, Chen M, Miner J, Fromm ME
Citation(s) 17878318
Submission date Aug 03, 2007
Last update date Feb 11, 2019
Contact name Jean-Jack M. Riethoven
Organization name University of Nebraska-Lincoln
Department Beadle Center for Biotechnology
Lab Bioinformatics Core Research Facility
Street address 1901 Vine Street
City Lincoln
State/province NE
ZIP/Postal code 68588-0665
Country USA
Platforms (1)
GPL1261 [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
Samples (25)
GSM215256 3T3-L1 adipocyte tissue culture, LA fed, T1, biological rep1
GSM215257 3T3-L1 adipocyte tissue culture, LA fed, T1, biological rep2
GSM215258 3T3-L1 adipocyte tissue culture, LA fed, T1, biological rep3
This SubSeries is part of SuperSeries:
GSE11384 Trans-10, cis-12 conjugated linoleic acid activates the integrated stress response pathway in adipocytes
BioProject PRJNA109033

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE8681_12hr_RosettaResolver_processed_ratio.xls 3.0 Mb (ftp)(http) XLS
GSE8681_24hr_RosettaResolver_processed_ratio.xls 3.0 Mb (ftp)(http) XLS
GSE8681_4hr_RosettaResolver_processed_ratio.xls 3.0 Mb (ftp)(http) XLS
GSE8681_8hr_RosettaResolver_processed_ratio.xls 3.0 Mb (ftp)(http) XLS
GSE8681_RAW.tar 81.8 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table
Processed data are available on Series record
Raw data provided as supplementary file

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