NCBI Logo
GEO Logo
   NCBI > GEO > Accession DisplayHelp Not logged in | LoginHelp
GEO help: Mouse over screen elements for information.
          Go
Series GSE8682 Query DataSets for GSE8682
Status Public on Jan 11, 2008
Title Gene expression in mouse 3T3-L1 adipocyte tissue culture treated with tunicamycin
Organism Mus musculus
Experiment type Expression profiling by array
Summary Tunycamcin induces UPR/ISR and Inflammation in mouse 3T3-L1 adipocyte tissue culture. The early transcriptome changes were analyzed using high-density microarrays to better characterize the signaling pathways responding to tunicamycin, to be compared with similar experiments with CLA as the treatment. Their gene expression responses between 4 to 12 hr after treatment showed a common set of early gene expression changes indicative of a UPR/Inflammation stress response.
Keywords: control/treatment time course
 
Overall design Mouse 3T3-L1 RNA for each time point was isolated from control and treatment samples for analysis on microarrays with two biological reps.
 
Contributor(s) LaRosa C, Riethoven JM, Chen H, Xia Y, Zhou Y, Chen M, Miner J, Fromm ME
Citation(s) 17878318
Submission date Aug 03, 2007
Last update date Feb 11, 2019
Contact name Jean-Jack M. Riethoven
E-mail(s) jeanjack@unl.edu
Organization name University of Nebraska-Lincoln
Department Beadle Center for Biotechnology
Lab Bioinformatics Core Research Facility
Street address 1901 Vine Street
City Lincoln
State/province NE
ZIP/Postal code 68588-0665
Country USA
 
Platforms (1)
GPL1261 [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
Samples (8)
GSM215285 3T3-L1 adipocyte tissue culture, control, T1, biological rep1
GSM215286 3T3-L1 adipocyte tissue culture, tunicamycin exposed, T1, biological rep1
GSM215287 3T3-L1 adipocyte tissue culture, control, T2, biological rep1
This SubSeries is part of SuperSeries:
GSE11384 Trans-10, cis-12 conjugated linoleic acid activates the integrated stress response pathway in adipocytes
Relations
BioProject PRJNA109035

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE8682_12hr_RosettaResolver_processed_ratio.xls 3.0 Mb (ftp)(http) XLS
GSE8682_4hr_RosettaResolver_processed_ratio.xls 3.0 Mb (ftp)(http) XLS
GSE8682_8hr_RosettaResolver_processed_ratio.xls 3.0 Mb (ftp)(http) XLS
GSE8682_RAW.tar 27.8 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table
Processed data are available on Series record
Raw data provided as supplementary file

| NLM | NIH | GEO Help | Disclaimer | Accessibility |
NCBI Home NCBI Search NCBI SiteMap