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Status |
Public on Dec 01, 2018 |
Title |
Gene expression profiling of mucosal biopsies from pediatric patients with moderately to severely active ulcerative colitis |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by array
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Summary |
To acquire a better understanding of the molecular pathogenesis of pediatric UC with different disease extent, we performed mRNA microarray studies to compare gene expression of patients with extensive UC vs. that of patients with limited UC. No significant difference was observed in mRNA expression between extensive and limited UC in pediatric patients.
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Overall design |
Mucosal biopsy samples (13 extensive and 6 limited UC) were collected for RNA extraction and microarray analysis.
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Contributor(s) |
Li K, Strauss R, Chan D, Brodmerkel C, Friedman JR |
Citation(s) |
29401083 |
Submission date |
Sep 29, 2016 |
Last update date |
Mar 02, 2019 |
Contact name |
K Li |
E-mail(s) |
kli@its.jnj.com
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Organization name |
Janssen R&D
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Street address |
1400 McKean Road
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City |
Spring House |
State/province |
PA |
ZIP/Postal code |
19477 |
Country |
USA |
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Platforms (1) |
GPL13158 |
[HT_HG-U133_Plus_PM] Affymetrix HT HG-U133+ PM Array Plate |
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Samples (19)
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This SubSeries is part of SuperSeries: |
GSE87473 |
Gene expression profiling of mucosal biopsies from pediatric or adult patients with moderately to severely active ulcerative colitis |
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Relations |
BioProject |
PRJNA344859 |