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Series GSE87842 Query DataSets for GSE87842
Status Public on Oct 25, 2016
Title Role of Gq/11 and G12/13 signalling in Type II alveolar epithelial cells
Organism Mus musculus
Experiment type Expression profiling by array
Summary We have used microarrays to identify individual genes and pathways regulated by Gq/11 or G12/13 signalling in type II alveolar epithelial cells isolated from the lungs of knockout mice.
 
Overall design Type II alveolar epithelial cells were isolated from the lungs of mice either singly deficient in Gna11 or Gna12 or double deficient in Gnaq/Gna11 or Gna12/Gna13 genes. Cells were cultured for 7 days and RNA processed from the untreated epithelial cells to compare gene expression patterns in cells from single and double knockout animals.
 
Contributor(s) John AE, Miele G
Citation(s) 27811142
Submission date Oct 11, 2016
Last update date Feb 11, 2019
Contact name Alison Elizabeth John
E-mail(s) alison.john@nottingham.ac.uk
Phone 01158231106
Organization name University of Nottingham
Department Respiratory Medicine
Street address Clinical Sciences Bulding, City Hospital Campus
City Nottingham
State/province NOTTS
ZIP/Postal code NG5 1PB
Country United Kingdom
 
Platforms (1)
GPL1261 [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
Samples (12)
GSM2341754 Gna11 ko ATII cell 1
GSM2341755 Gna11 ko ATII cell 2
GSM2341756 Gna11 ko ATII cell 3
Relations
BioProject PRJNA347839

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE87842_RAW.tar 45.0 Mb (http)(custom) TAR (of CEL, CHP)
Raw data provided as supplementary file
Processed data included within Sample table
Processed data provided as supplementary file

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