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Series GSE8800 Query DataSets for GSE8800
Status Public on Dec 29, 2007
Title Expression data from embryos injected with DrC1q-like morpholino and control morpholino
Organism Danio rerio
Experiment type Expression profiling by array
Summary Except complement C1q, the immunological functions of other C1q family members have remained unclear. In vitro studies showed that DrC1q-like could inhibit the apoptosis induced by ActD and CHX in EPC cells, through repressing the activation of caspase 3/9. Moreover, its physiological roles were studied by morpholino-mediated knockdown in zebrafish embryogenesis
We used microarrays to compare the global programme of gene expression of DrC1q-like deficient embryos and control embryos. And identified distinct classes of up-regulated and down-regulated genes in DrC1q-like deficient embryos.
Keywords: time course
 
Overall design Zebrafish embryos were selected at 24hpf for RNA extraction and hybridization on Affymetrix microarrays. We sought to obtain expression profiles of DrC1q-like deficient embryos compared to the control. And we could find out which genes and pathways were affected by DrC1q-like
 
Contributor(s) Mei J, Gui J
Citation(s) 18514183
Submission date Aug 16, 2007
Last update date Jan 25, 2018
Contact name Jie Mei
E-mail(s) kevinmei@ihb.ac.cn
Organization name Institute of Hydrobiology
Department Chinese Academy of Sciences
Lab Wuhan Center for Developmental Biology
Street address 7# Donghu South Road
City Wuhan
State/province Hubei
ZIP/Postal code 430072
Country China
 
Platforms (1)
GPL1319 [Zebrafish] Affymetrix Zebrafish Genome Array
Samples (2)
GSM218665 MO
GSM218666 Cont MO
Relations
BioProject PRJNA102105

MO vs Cont MO header descriptions
Probe Set ID
MO vs Cont MO_Signal Log Ratio
MO vs Cont MO_Signal Log Ratio Low
MO vs Cont MO_Signal Log Ratio High
MO vs Cont MO_Change
MO vs Cont MO_Change p-value
Gene Title
Gene Symbol

Data table
Probe Set ID MO vs Cont MO_Signal Log Ratio MO vs Cont MO_Signal Log Ratio Low MO vs Cont MO_Signal Log Ratio High MO vs Cont MO_Change MO vs Cont MO_Change p-value Gene Title Gene Symbol
Dr.1.1.S1_at 0.2 -0.5 1.0 NC 0.500000 myelocytomatosis oncogene a myca
Dr.10.1.S1_at -0.2 -0.9 0.5 NC 0.500000 paired box gene 2a pax2a
Dr.10.4.S1_a_at 1.4 0.9 1.8 NC 0.018966 paired box gene 2a pax2a
Dr.100.1.A1_at -0.1 -1.0 0.7 NC 0.869055 ATP-binding cassette, sub-family A (ABC1), member 12 abca12
Dr.1000.1.S1_at -0.1 -0.5 0.3 NC 0.778357 high density lipoprotein-binding protein (vigilin) hdlbp
Dr.10000.1.A1_at 1.3 0.5 2.2 NC 0.151871 Transcribed locus, weakly similar to XP_225336.3 similar to CARMIL [Rattus norvegicus] ---
Dr.10005.1.A1_at -1.4 -2.0 -0.8 D 0.999981 Transcribed locus ---
Dr.10006.1.A1_at -0.2 -0.5 0.2 NC 0.919605 zgc:112077 /// similar to ubiquitin-conjugating enzyme E2G 2 zgc:112077 /// LOC573949
Dr.10010.1.A1_at 0.8 0.3 1.4 NC 0.250422 similar to HBxAg transactivated protein 2 LOC561451
Dr.10011.1.A1_at -0.1 -0.7 0.5 NC 0.544665 zgc:86658 zgc:86658
Dr.10012.1.A1_at -1.6 -2.3 -0.9 D 0.998696 wu:fk83g11 wu:fk83g11
Dr.10014.1.A1_at 1.5 0.9 2.1 NC 0.425834 similar to CG5263-PA, isoform A LOC559817
Dr.10015.1.S1_at 0.0 -2.1 2.1 NC 0.500000 similar to Transmembrane protease, serine 13 (Mosaic serine protease) (Membrane-type mosaic serine protease) LOC564843
Dr.10015.2.S1_a_at 1.8 0.5 3.1 NC 0.306825 similar to Transmembrane protease, serine 13 (Mosaic serine protease) (Membrane-type mosaic serine protease) /// similar to Transmembrane protease, serine 13 (Mosaic serine protease) (Membrane-type mosaic serine protease) LOC564693 /// LOC564843
Dr.10015.2.S1_at 1.1 0.3 1.8 NC 0.354210 similar to Transmembrane protease, serine 13 (Mosaic serine protease) (Membrane-type mosaic serine protease) /// similar to Transmembrane protease, serine 13 (Mosaic serine protease) (Membrane-type mosaic serine protease) LOC564693 /// LOC564843
Dr.10016.1.A1_at 0.7 0.3 1.1 NC 0.077641 zgc:77556 zgc:77556
Dr.10018.1.S1_at 2.5 0.7 4.3 NC 0.128962 Transcribed locus, weakly similar to XP_221091.4 similar to CLM3 [Rattus norvegicus] ---
Dr.1002.1.S1_at 0.5 0.2 0.7 NC 0.134962 similar to RIKEN cDNA 2310016M24 LOC568423
Dr.10022.1.S1_at -0.4 -0.9 0.1 NC 0.767078 bromodomain and PHD finger containing, 1 brpf1
Dr.10023.1.A1_at 0.7 -0.2 1.5 NC 0.500000 similar to CG7512-PA LOC559053

Total number of rows: 15502

Table truncated, full table size 1233 Kbytes.




Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE8800_RAW.tar 6.0 Mb (http)(custom) TAR (of CEL, EXP)
Raw data provided as supplementary file
Processed data included within Sample table
Processed data are available on Series record

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