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Series GSE8871 Query DataSets for GSE8871
Status Public on Feb 01, 2008
Title Human Breast Cancer Cell Lines: Control vs. Fn14 or Luciferase siRNA Treated
Organism Homo sapiens
Experiment type Expression profiling by array
Summary We performed gene expression profiling on the MDA-MB-231 and MDA-MB-436 human breast cancer cell lines following siRNA-mediated inhibition of Fn14 expression as an approach to identify the mechanistic basis for Fn14 regulation of invasive capacity.
Keywords: siRNA-mediated inhibition
 
Overall design Each cell lines was transfected with etiher an Fn14 or firefly luciferase-specific (GL2) siRNA, with untreated cells used as a reference. 2 biological replicates were performed for each array, independently grown, treated and harvested.
 
Contributor(s) Willis AL, Cunliffe HE
Citation(s) 18505918
Submission date Aug 24, 2007
Last update date Dec 06, 2012
Contact name Heather E Cunliffe
E-mail(s) hcunliffe@tgen.org
Phone 602-343-8811
URL http://www.tgen.org
Organization name Translational Genomics Research Institute
Department Cancer and Cell Biology
Lab Breast and Ovarian Cancer Research Unit
Street address 445 N 5th Street
City Phoenix
State/province AZ
ZIP/Postal code 85004
Country USA
 
Platforms (1)
GPL887 Agilent-012097 Human 1A Microarray (V2) G4110B (Feature Number version)
Samples (8)
GSM224782 MDA-MB-231 Fn14 siRNA Replicate 1
GSM224783 MDA-MB-231 Fn14 siRNA Replicate 2
GSM224784 MDA-MB-231 GL1 siRNA Replicate 1
Relations
BioProject PRJNA102239

Genes that were significant in Fn14 siRNA treatment arrays and non-significant in the GL2 siRNA control arrays header descriptions
ID_REF
GSM224782
GSM224783
GSM224784
GSM224785
GSM224786
GSM224787
GSM224788
GSM224789

Data table
ID_REF GSM224782 GSM224783 GSM224784 GSM224785 GSM224786 GSM224787 GSM224788 GSM224789
5 -1.027713507 -0.651097907 -0.143314013 0.109778784 -1.259702376 -1.237567771 0.045023208 -0.020685436
44 -0.786412749 -0.76736539 0.233147012 0.250455643 -1.032208119 -1.014115981 0.272293312 0.294263643
134 0.212061115 0.29199748 0.162742926 0.150187063 -0.595376764 -0.703214727 -0.179003384 0.037721517
282 -0.154316425 -0.117928447 0.094985992 0.061557447 0.937496421 1.194286111 0.472880848 0.459662326
351 -0.419012546 -0.375377875 -0.303679414 -0.246695783 -0.674876585 -0.815074943 -0.273147866 -0.229293229
673 0.607128489 0.594625129 0.12209509 0.13772626 0.432224805 0.524076999 -0.039959917 -0.050090441
734 -0.287089 -0.554761992 -0.155300615 -0.376368796 -0.586435167 -0.909650497 -0.385088619 -0.36015979
809 0.625238111 0.50493307 0.102704701 -0.014510798 0.870469332 0.701011537 -0.036448794 -0.019123502
980 0.570203562 0.641132122 0.417093963 0.44972752 0.692427898 0.660807442 0.218059343 0.247255731
1034 0.734160278 0.677673331 0.517219285 0.437652446 0.290822597 0.40261202 0.296942866 0.339195022
1234 -0.079757366 -0.123907918 0.206613655 0.123570158 -0.638052231 -0.947742779 0.036655691 -0.065705268
1560 0.823068852 0.750755749 0.219297257 0.276761887 0.912086478 0.950888619 0.189742002 0.19660858
1730 1.021237605 0.817194311 0.490697328 0.387595303 1.123252443 1.07763669 0.465160495 0.489114767
1754 -0.893223809 -0.873667089 -0.239316309 -0.109627403 -1.049632574 -0.86197747 -0.138146444 -0.157096836
1782 -0.287349775 -0.251137764 0.162843536 0.250543955 -0.584951949 -0.777431511 -0.088333746 0.002082908
1864 -0.548866328 -0.524864639 -0.410986695 -0.406695811 -0.603180093 -0.671199057 -0.386897513 -0.457179809
1978 -0.373465918 -0.587981273 0.440180239 0.171257569 -0.783165944 -0.905702876 0.541671274 0.469733097
2119 0.305260859 0.02541275 0.066181131 0.024682391 0.597729217 0.577658721 0.357025009 0.331378222
2127 -0.65156888 -0.607912841 -0.208033447 -0.10775249 -0.913119117 -1.010187036 -0.204184413 -0.081674474
2892 0.518646009 0.1524765 0.482482846 0.350533365 0.595206127 0.594202674 0.502583775 0.41798501

Total number of rows: 161

Table truncated, full table size 16 Kbytes.




Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE8871_RAW.tar 49.8 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table

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