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| Status |
Public on Oct 31, 2018 |
| Title |
Transcript profiling in peritoneal macrophages from wildtype or c-JunΔLysM mice |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
The polarization and activation of macrophages are controlled synergistically by transcription factors such as NF-κB and AP-1 transcription factor members. Surprisingly, little is known about the role of the AP-1 transcription factor c-Jun in macrophage activity. To determine the full profile of c-Jun network, microarray RNA expression analysis using Agilent Technologies platform was performed in wild-type and c-JunΔLysM macrophages.
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| Overall design |
For microarray analyses, peritoneal macrophages were collected by peritoneal lavage of 8 week old wild-type (n=3) or c-JunΔLysM mice (n=2). Peritoneal cells were plated over night. The next day, suspension cells were removed and only adherent cells were used for RNA isolation.
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| Contributor(s) |
Hannemann N, Reid S, Sonnewald S, Bozec A |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Oct 18, 2016 |
| Last update date |
Nov 01, 2018 |
| Contact name |
Aline Bozec |
| Organization name |
Universitätsklinikum Erlangen, Department of Internal Medicine 3 – Rheumatology and Immunology
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| Lab |
Aline Bozec
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| Street address |
Ulmenweg 18
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| City |
Erlangen |
| ZIP/Postal code |
91054 |
| Country |
Germany |
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| Platforms (1) |
| GPL10787 |
Agilent-028005 SurePrint G3 Mouse GE 8x60K Microarray (Probe Name version) |
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| Samples (5)
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| Relations |
| BioProject |
PRJNA349038 |
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