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| Status |
Public on Oct 21, 2016 |
| Title |
Gene expression profiling of differentially treated hematopoietic stem cells (LSK SLAM) |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
Expression prolile of POL5551 treated (continuos infusion, 2 wks, 100 mg/kg/day) HSC was compared to that of G-CSF (100 ug/kg/injection, q12h, 2 vs. 5 days) and sham-op treated cells in order to identify potential inherent differences between the specimen. The cells were isolated from the BM of differentially treated mice.
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| Overall design |
Mice were treated with G-CSF (2 days and 5 days), POL5551 (2 wks) or sham-op. BM was isolated and enriched for kit (CD117)+ progenitors and LSK SLAM cells (HSC) were then flow sorted from the positive cell fraction.
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| Contributor(s) |
Karpova D, Monlish D |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Oct 20, 2016 |
| Last update date |
Mar 22, 2017 |
| Contact name |
Darja Karpova |
| E-mail(s) |
d.karpova@wustl.edu
|
| Phone |
+1-314-362-9335
|
| Organization name |
Washington University School of Medicine
|
| Department |
Oncology, BMT
|
| Lab |
John F. DiPersio
|
| Street address |
660 S Euclid Ave
|
| City |
St. Louis |
| State/province |
MO |
| ZIP/Postal code |
63110 |
| Country |
USA |
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| Platforms (1) |
| GPL21163 |
Agilent-074809 SurePrint G3 Mouse GE v2 8x60K Microarray [Probe Name version] |
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| Samples (12)
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| Relations |
| BioProject |
PRJNA349486 |
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