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| Status |
Public on Nov 04, 2016 |
| Title |
Gene expression from ErbB2KI tumors with a heterozygous or a homoszygous loss of beta-catenin (ctnnb1) |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
Beta-catenin controls both cell adhesion and transcription to facilitate ErbB2-driven mammary tumorigenesis
In this study, we used conditional knockout and gene expression approaches to understand global molecular and transciptional changes due to ablation of both functions of beta-catenin.
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| |
|
| Overall design |
Beta-catenin (ctnnb1) was specifically deleted in the mammary epithelium of ErbB2KI mice. Total RNA was collected from end-burden tumors (flash frozen) and subjected to microarray gene expression.
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| |
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| Contributor(s) |
Bui T, Schade B |
| Citation(s) |
28096336 |
| Submission date |
Nov 03, 2016 |
| Last update date |
Feb 21, 2018 |
| Contact name |
Tung Bui |
| E-mail(s) |
tung.bui@mail.mcgill.ca
|
| Organization name |
McGill University
|
| Department |
Biochemistry
|
| Lab |
William Muller
|
| Street address |
1160 Pine Ave. W, R507
|
| City |
Montreal |
| State/province |
Quebec |
| ZIP/Postal code |
H3A 1A3 |
| Country |
Canada |
| |
|
| Platforms (1) |
| GPL16570 |
[MoGene-2_0-st] Affymetrix Mouse Gene 2.0 ST Array [transcript (gene) version] |
|
| Samples (15)
|
|
| Relations |
| BioProject |
PRJNA352404 |
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