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Status |
Public on Dec 31, 2017 |
Title |
In vitro Exon Level Expression Profiling of dermal fibroblast |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by array
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Summary |
Transcriptome analysis of of control inhibitor and miR200b inhibitor transfected Human Dermal Adult Fibroblasts (HDAF) compared with Human Dermal Microvascular Endothelial Cells (HMEC). Injury induced inhibition of miR200b induces angiogenesis at the wound edges which help in the healing process. We have characterised the effect of miR200b suppression in Human Adult Dermal Fibroblasts converts to endothelial cells through transcriptional profiling. In this dataset, we include the expression data obtained from control inhibitor and miR200b inhibitor transfected Human Dermal Adult Fibroblasts, as well as Human Dermal Microvascular Endothelial Cells (HMEC) as positive control.
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Overall design |
9 total samples were analyzed by using the Affymetrix GeneChip® Human Transcriptome Array 2.0
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Contributor(s) |
Durba P, Subhadip G, Kanhaiya S, Sashwati R, Natalia CH, Savita K, Daniel PG, Chandan SK |
Citation missing |
Has this study been published? Please login to update or notify GEO. |
Submission date |
Nov 09, 2016 |
Last update date |
Oct 29, 2018 |
Contact name |
Chandan K Sen |
E-mail(s) |
Chandan.Sen@osumc.edu
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Organization name |
Ohio State University Wexner Medical Center
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Department |
Surgery
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Lab |
DHLRI
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Street address |
473W. 12th Avenue,
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City |
Columbus |
State/province |
Ohio |
ZIP/Postal code |
43210 |
Country |
USA |
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Platforms (1) |
GPL17586 |
[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version] |
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Samples (9)
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GSM2387237 |
Human Dermal Adult Fibroblasts, transfected with control inhibitor-1 |
GSM2387238 |
Human Dermal Adult Fibroblasts, transfected with control inhibitor-2 |
GSM2387239 |
Human Dermal Adult Fibroblasts, transfected with control inhibitor-3 |
GSM2387240 |
Human Dermal Adult Fibroblasts, transfected with miR-200b inhibitor-1 |
GSM2387241 |
Human Dermal Adult Fibroblasts, transfected with miR-200b inhibitor-2 |
GSM2387242 |
Human Dermal Adult Fibroblasts, transfected with miR-200b inhibitor-3 |
GSM2387243 |
Human Dermal Microvascular Endothelial Cells-1 |
GSM2387244 |
Human Dermal Microvascular Endothelial Cells-2 |
GSM2387245 |
Human Dermal Microvascular Endothelial Cells-3 |
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Relations |
BioProject |
PRJNA352994 |
Supplementary file |
Size |
Download |
File type/resource |
GSE89715_RAW.tar |
204.3 Mb |
(http)(custom) |
TAR (of CEL, CHP) |
Processed data included within Sample table |
Processed data provided as supplementary file |
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