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Series GSE89851 Query DataSets for GSE89851
Status Public on Mar 23, 2018
Title The effect of new probiotic mixture in DSS (dextran sulphate sodium) – induced colitis mouse model
Organism Mus musculus
Experiment type Expression profiling by array
Summary The current study was designed to clarify signalling pathways and assess possible beneficial effect of new probiotic mixture in DSS (dextran sulphate sodium) – induced colitis mouse model. Manipulation of intestinal microbiota with probiotics represents a promising alternative or adjunct therapy in gastrointestinal disorders and inflammation.
RNA extracted from the middle part of colon tissue from ~11 weeks female C57BL/6JOlaHsd mouse strain was used for examination of the global gene expression using Affymetrix GeneChip Mouse Gene 2.0 ST microarrays.
 
Overall design Two factor experimental design: two conditions (Healthy and DSS-induced colitis) and three treatments (None-saline, Probiotic, CsA-cyclosporine A), w/o CsA treatment of healthy animals. 4 biological replicates per condition, 20 mice altogether.
 
Contributor(s) Juvan P, Košir R, Paveljšek D, Rogelj I
Citation(s) 29633647
Submission date Nov 15, 2016
Last update date Apr 16, 2018
Contact name Peter Juvan
Phone +386 1 543 7595
Organization name Faculty of Medicine, University of Ljubljana
Department Institute of Biochemistry
Lab Center for Functional Genomics and Bio-Chips
Street address Zaloska 4
City Ljubljana
ZIP/Postal code SI-1000
Country Slovenia
 
Platforms (1)
GPL16570 [MoGene-2_0-st] Affymetrix Mouse Gene 2.0 ST Array [transcript (gene) version]
Samples (20)
GSM2391508 Mm_colon_Healthy_None_rep02
GSM2391509 Mm_colon_Healthy_None_rep04
GSM2391510 Mm_colon_Healthy_None_rep06
Relations
BioProject PRJNA353599

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE89851_RAW.tar 185.3 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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