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Series GSE90003 Query DataSets for GSE90003
Status Public on Feb 01, 2021
Title Mapping nucleolus-associated chromatin interactions by nucleolus-Hi-C reveals repression network
Organism Homo sapiens
Experiment type Other
Summary Nucleolus plays a key role in organizing global nuclear structure and facilitating gene regulation, but the three dimensional information within the nucleolus associated chromatins are still unknown, so here we development the Nucleolus Hi-C (NHi-C) experimental technique, which combines the nucleolus isolation with Hi-C experiment, and study the interactions within and surrounding nucleolus in human cells with a high resolution. With NHi-C experiment, we report how the nucleolus-associated chromatin regions interact at genome scale, and how these interactions organize the repressive nucleus architecture.
 
Overall design in situ Hi-C and Nucleolus Hi-C data in human cells to detect the 3D genome information, the detailed information about all files uploaded to GEO for this study are explained in "DataFiles.README"
 
Contributor(s) Li T, Meng H, Li C
Citation(s) 36681699
Submission date Nov 17, 2016
Last update date Feb 07, 2023
Contact name Howard MENG
E-mail(s) menghaowei@pku.edu.cn
Organization name Peking University
Department School of Life Sciences
Lab Yi Chengqi Lab
Street address No.5 Yiheyuan Road Haidian District
City Beijing
State/province Beijing
ZIP/Postal code 100871
Country China
 
Platforms (1)
GPL20795 HiSeq X Ten (Homo sapiens)
Samples (22)
GSM2395401 HeLa in situ Hi-C rep1
GSM2395402 HeLa in situ Hi-C rep2
GSM2395403 HeLa in situ Hi-C rep3
Relations
BioProject PRJNA354332
SRA SRP093665

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE90003_DataFiles.README.txt 1.4 Kb (ftp)(http) TXT
GSE90003_Hela-hic-ActD_MAPQ20_RawMatrix.tar.gz 348.6 Mb (ftp)(http) TAR
GSE90003_Hela-hic_MAPQ20_RawMatrix.tar.gz 941.9 Mb (ftp)(http) TAR
GSE90003_Hela-n-hic_MAPQ20_RawMatrix.tar.gz 900.3 Mb (ftp)(http) TAR
GSE90003_U2OS-n-hic_MAPQ20_RawMatrix.tar.gz 691.0 Mb (ftp)(http) TAR
SRA Run SelectorHelp
Raw data are available in SRA
Processed data are available on Series record

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