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GEO help: Mouse over screen elements for information. |
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| Status |
Public on Dec 01, 2016 |
| Title |
Expression data of GMDCs with conditioned medium from topotecan-treated E0771 cells |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
Danger-associated molecular patterns (DAMPs) derived from damaged or dying cells not only elicit inflammation but also potentiate antitumor immune responses. Here, we show that treatment of breast cancer cells with the antitumor agent Topotecan, an inhibitor of topoisomerase I, induces DAMP secretion that triggers dendritic cell activation and cytokine production.
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| Overall design |
To investigate the gene expression of GMDC that were cultured with the conditioned medium from topotecan-treated cells
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| Contributor(s) |
Kitai Y, Kawasaki T, Sueyoshi T, Kobiyama K, Ishii K, Jian Z, Akira S, Kawai T |
| Citation(s) |
28069806 |
| Submission date |
Nov 18, 2016 |
| Last update date |
Feb 21, 2018 |
| Contact name |
Yuichi Kitai |
| E-mail(s) |
yu-kitai@pharm.hokudai.ac.jp
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| Organization name |
Hokkaido University
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| Department |
Faculty of Pharmaceutical Sciences
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| Street address |
N12 W6, Kita-ku
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| City |
Sapporo |
| ZIP/Postal code |
060-0812 |
| Country |
Japan |
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| Platforms (1) |
| GPL16570 |
[MoGene-2_0-st] Affymetrix Mouse Gene 2.0 ST Array [transcript (gene) version] |
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| Samples (2) |
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| Relations |
| BioProject |
PRJNA354403 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE90042_RAW.tar |
16.7 Mb |
(http)(custom) |
TAR (of CEL, CHP) |
| Processed data included within Sample table |
| Processed data provided as supplementary file |
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