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| Status |
Public on Oct 23, 2017 |
| Title |
Genome-wide analysis of Nrdc-binding sites by ChIP-seq in mouse embryonic fibroblasts |
| Organism |
Mus musculus |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
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| Summary |
Nardilysin (Nrdc) is a metallopeptidase of M16 family, which has been recently identified as a transcriptional coregulator. Here, we characterize the role of Nrdc in transcriptional regulation by genome-wide analysis using ChIP-seq and transcriptome.
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| Overall design |
Nrdc-binding sites and histone modifications were examined by ChIP-seq in immortalized mouse embryonic fibroblasts (MEF). MEFs generated from wild-type (+/+) and Nrdc-deficient (-/-) mice were used. MEF-/- cells, in which Nrdc was reintroduced by lenti-virus vector, were also used as control.
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| Contributor(s) |
Yusuke M, Eiichiro N |
| Citation(s) |
29093577 |
| Submission date |
Nov 21, 2016 |
| Last update date |
Jul 09, 2019 |
| Contact name |
Yusuke Morita |
| E-mail(s) |
ysmorita@kuhp.kyoto-u.ac.jp
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| Organization name |
kyoto university
|
| Street address |
kyoto
|
| City |
kyoto |
| State/province |
kyoto |
| ZIP/Postal code |
5360015 |
| Country |
Japan |
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| Platforms (1) |
| GPL18635 |
Ion Torrent Proton (Mus musculus) |
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| Samples (11)
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| This SubSeries is part of SuperSeries: |
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| Relations |
| BioProject |
PRJNA354481 |
| SRA |
SRP093763 |
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