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Series GSE9012 Query DataSets for GSE9012
Status Public on Nov 19, 2007
Title Expression data from spontaneous liver tumors of Trim24/TIF1a-null mice.
Organism Mus musculus
Experiment type Expression profiling by array
Summary The transcriptional coregulator Trim24 (formerly known as TIF1a) functions in mice as a liver-specific tumor suppressor. Mice carrying a null mutation in the Trim24 gene all develop hepatocellular carcinoma (HCC).
We used microarrays to identify the alterations in gene expression patterns associated with loss of Trim24 and consequent HCC development.
Keywords: normal-tumor comparison
 
Overall design Five independent liver tumor (HCC) samples taken from five Trim24 knockout (KO) mice and five normal liver tissue samples taken from wild-type (WT) littermate controls were used for RNA extraction and hybridization on Affymetrix microarrays.
 
Contributor(s) Khetchoumian K, Tisserand J, Losson R
Citation(s) 18026104
Submission date Sep 11, 2007
Last update date Feb 11, 2019
Contact name RĂ©gine Losson
E-mail(s) losson@igbmc.u-strasbg.fr
Organization name IGBMC
Street address 1 rue Laurent Fries
City ILLKIRCH CEDEX
ZIP/Postal code 67404
Country France
 
Platforms (1)
GPL1261 [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
Samples (10)
GSM228781 HCC_KO_rep1
GSM228782 HCC_KO_rep2
GSM228783 HCC_KO_rep3
Relations
BioProject PRJNA102499

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE9012_RAW.tar 169.2 Mb (http)(custom) TAR (of CEL, CHP, EXP)
Raw data provided as supplementary file
Processed data included within Sample table
Processed data provided as supplementary file

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