|
Status |
Public on Jun 20, 2017 |
Title |
TCF7L1 knockdown in pancreatic cancer |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by high throughput sequencing
|
Summary |
RNAi mediated depletion of TCF7L1 increases activity of a Wnt-based reporter and imparts more aggressive tumor phenotypes in vitro in pancreatic cancer cell lines that express TCF7L1. We sought to determine what changes in transcription ocurred after RNAi mediated knockdown of TCF7L1 in these cells by RNA-sequencing
|
|
|
Overall design |
12 samples, 4 different conditions with 3 replicates each
|
|
|
Contributor(s) |
David D, Kathleen K |
Citation missing |
Has this study been published? Please login to update or notify GEO. |
Submission date |
Dec 06, 2016 |
Last update date |
May 15, 2019 |
Contact name |
David Dawson |
Organization name |
UCLA
|
Department |
Pathology
|
Lab |
Dawson
|
Street address |
650 Charles E Young Dr South
|
City |
Los Angeles |
State/province |
California |
ZIP/Postal code |
90095 |
Country |
USA |
|
|
Platforms (1) |
GPL21290 |
Illumina HiSeq 3000 (Homo sapiens) |
|
Samples (12)
|
|
Relations |
BioProject |
PRJNA356377 |
SRA |
SRP094619 |