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Status |
Public on Apr 10, 2017 |
Title |
Gene expression in the anterior cingulate cortex in mice treated with ketamine (3mg/kg) or sleep deprivation (SD) during 12 hrs., and saline as the control group. |
Organism |
Mus musculus |
Experiment type |
Expression profiling by array
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Summary |
Both, sleep deprivation and ketamine treatments are efficient and fast-acting antidepressants acting within the first 12-24 hr. post-treatment. This experiment was designed to identify if common transcriptional responses are elicited by both treatments
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Overall design |
Mice were divided into 3 groups and administered either: A) KT (3mg/kg i.p at ZT5; B) saline [100 μl/0.03kg i.p.] at ZT 5; (control) or C) SD (animals were kept awake from ZT 0 to ZT 12). All groups were euthanized at ZT 13.
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Contributor(s) |
Orozco-Solis R, Sassone-Corsi P |
Citation(s) |
28395871 |
Submission date |
Dec 31, 2016 |
Last update date |
Dec 06, 2022 |
Contact name |
Ricardo Orozco-Solis |
E-mail(s) |
drorozcos@inmegen.gob.mx
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Phone |
525535229714
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Organization name |
Instituto Nacional de Medicina Genomica
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Street address |
Periférico Sur 4809, Arenal Tepepan
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City |
Ciudad de México |
State/province |
TLALPAN |
ZIP/Postal code |
14610 |
Country |
Mexico |
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Platforms (1) |
GPL16570 |
[MoGene-2_0-st] Affymetrix Mouse Gene 2.0 ST Array [transcript (gene) version] |
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Samples (9)
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Relations |
BioProject |
PRJNA359575 |