|
| Status |
Public on May 05, 2017 |
| Title |
Transcriptome characterization of IFNa response in MaSC and luminal progenitor cells |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
Transcriptome response to IFNa treatment in MaSC, Luminal progenitor cells were studied. The MaSC, Luminal progenitor cells enriched subpopulations were sorted based on CD24/CD29 expression from mammary epithelial cells of virgin female mice . (Tiede BJ et al., 2009, PLoS ONE 4(11): e8035. doi:10.1371/journal.pone.0008035). The cells were cultured in mammosphere condition in vitro and treated with Ifna for 8 days. The total RNA samples are collected and compared using microarray analysis.
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| |
|
| Overall design |
2x2 design. Comparison of two subpopulations MaSC (P4) and Luminal progenitor (P5) enriched subpopulations and two treatment conditions, control and IFNa treated.
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| |
|
| Contributor(s) |
Celià-Terrassa T, Wei Y |
| Citation(s) |
28530657 |
| Submission date |
Jan 03, 2017 |
| Last update date |
Feb 29, 2024 |
| Contact name |
Yong Wei |
| E-mail(s) |
yongwei@princeton.edu
|
| Organization name |
Princeton University
|
| Department |
Molecular Biology
|
| Lab |
Kang
|
| Street address |
LTL227 Wathington Road
|
| City |
Plainsboro |
| State/province |
NJ |
| ZIP/Postal code |
08536 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL10787 |
Agilent-028005 SurePrint G3 Mouse GE 8x60K Microarray (Probe Name version) |
|
| Samples (8)
|
| GSM2443346 |
Subpopulation P4 (CD24+CD29hi) from virgin wild type FVB mice, control replicate 1 |
| GSM2443347 |
Subpopulation P4 (CD24+CD29hi) from virgin wild type FVB mice, IFNa treated replicate 1 |
| GSM2443348 |
Subpopulation P5 (CD24+CD29hi) from virgin wild type FVB mice, control replicate 1 |
| GSM2443349 |
Subpopulation P5 (CD24+CD29hi) from virgin wild type FVB mice, IFNa treated replicate 1 |
| GSM2443350 |
Subpopulation P4 (CD24+CD29hi) from virgin wild type FVB mice, control replicate 2 |
| GSM2443351 |
Subpopulation P4 (CD24+CD29hi) from virgin wild type FVB mice, IFNa treated replicate 2 |
| GSM2443352 |
Subpopulation P5 (CD24+CD29hi) from virgin wild type FVB mice, control replicate 2 |
| GSM2443353 |
Subpopulation P5 (CD24+CD29hi) from virgin wild type FVB mice, IFNa treated replicate 2 |
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| This SubSeries is part of SuperSeries: |
| GSE85808 |
miR-199a-LCOR axis regulation of mammary gland stem cell and breast cancer stem cell transcriptional programs |
|
| Relations |
| BioProject |
PRJNA359766 |
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