|
| Status |
Public on Jan 13, 2018 |
| Title |
Genome-wide analysis of HDAC9 and BRG1 protein-RNA interactions in TAA by CLIP-seq |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
We analyze the protein-RNA interactions of HDAC9 and BRG1 in human aortic smooth muscle cells overexpressing mutant aneurysm alleles (TGFBR2G357W and ACTA2R179H) and wild-type cells using CLIP-seq.
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| |
|
| Overall design |
Determination of HDAC9 and BRG1 interaction with RNAs during the aneurysm state in vitro.
|
| |
|
| Contributor(s) |
Lino Cardenas CL, Lindsay ME |
| Citation(s) |
29520069 |
| NIH grant(s) |
| Grant ID |
Grant title |
Affiliation |
Name |
| R01 HL130113 |
The Role of HDAC9/MITR in the Pathogenesis of Thoracic Aortic Aneurysm (TAA) |
MASSACHUSETTS GENERAL HOSPITAL |
MARK E LINDSAY |
|
| Submission date |
Jan 17, 2017 |
| Last update date |
May 15, 2019 |
| Contact name |
christian lacks lino cardenas |
| E-mail(s) |
clinocardenas@mgh.harvard.edu
|
| Phone |
4127993484
|
| Organization name |
Massachusetts general hospital-Harvard medical school
|
| Department |
division of cardiovascular
|
| Lab |
Lindsay
|
| Street address |
185 Cambridge st Room 3224
|
| City |
Boston |
| State/province |
Massachusetts |
| ZIP/Postal code |
02114 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL20301 |
Illumina HiSeq 4000 (Homo sapiens) |
|
| Samples (6)
|
|
| Relations |
| BioProject |
PRJNA362243 |
| SRA |
SRP096920 |
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