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Series GSE9424 Query DataSets for GSE9424
Status Public on Sep 13, 2010
Title Assessing Statistical Significance in Microarray Experiments Using the Distance Between Microarrays
Organism Mus musculus
Experiment type Expression profiling by array
Summary We propose a method to compare the location and variability of gene ex-pression between two groups of microarrays using a permutation test based on the pairwise distance between microarrays. The microarrays could be samples from distinct clinical or biological populations or microarrays prepared at two different levels of an experimental factor. For these tests the entire microarray or some pre-specifed subset of genes, not the individual gene, is the unit of analysis. We apply this method to compare results from two dfferent protocols for preparing labeled targets for microarray hybridization and their subsequent gene expression analysis.
Keywords: Comparative genomic expression
Overall design Overall design - Splenocytes were extracted from six sham mice and six trauma-hemorrhagic mice. Total RNA was prepared from individual mice and labeled as targets by two different methods for analysis on Affymentrix MOE 430 2+chips.
Web link
Contributor(s) Hayden D, Brownstein BH, Lazar P, Schoenfeld D
Citation(s) 19529777
Submission date Oct 24, 2007
Last update date Feb 11, 2019
Contact name Wenzhong Xiao, Inflammation & the Host Response to Injury
Phone 617 726 0082
Organization name Massachusetts General Hospital
Department Department of Surgery
Lab Burn & Trauma Research
Street address 55 Fruit Street, GRV 1302
City Boston
State/province MA
ZIP/Postal code 02114
Country USA
Platforms (1)
GPL1261 [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
Samples (24)
GSM239538 n844sh_135915
GSM239539 n845sh_135916
GSM239540 n846sh_135917
BioProject PRJNA103167

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Supplementary file Size Download File type/resource
GSE9424_RAW.tar 138.7 Mb (http)(custom) TAR (of CEL)
Raw data provided as supplementary file
Processed data included within Sample table

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