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Series GSE9442 Query DataSets for GSE9442
Status Public on Dec 07, 2007
Title Molecular correlates of sleep deprivation in the brain of three inbred mouse strains in an around-the-clock experiment
Organism Mus musculus
Experiment type Expression profiling by array
Summary These studies adress differential changes in gene expression between sleep deprived and control mice. We profiled gene expression at four time points across the 24H Light/Dark cycle to take into account circadian influences and used three different inbred strains to understand the influence of genetic background.
Keywords: brain, circadian, genetic background, sleep deprivation
Overall design Experiments were performed on male mice ( AKR/J (A), C57BL/6J (B), DBA/2J (D)), 12-13 weeks of age, purchased from Jackson Laboratory. Animals were housed in a light/dark cycle of 24 hrs with water and food available ad libitum. Mice of the 3 inbred strains were sleep deprived for 6h starting at light onset (ZT0), at the middle of the light (ZT6), at the beginning of the dark (ZT12), or at the middle of the dark (ZT18) period, and sacrificed together with their home-cage controls (n=9 / strain =3 / time =4 / condition =2; total =216 mice).
Contributor(s) Dorsaz S, Petit B, Pradervand S, Franken P, Tafti M
Citation(s) 18077435
Submission date Oct 26, 2007
Last update date Feb 11, 2019
Contact name Mehdi Tafti
Phone +41216923971
Organization name University of Lausanne
Department CIG
Street address Genopode
City Lausanne
ZIP/Postal code 1015
Country Switzerland
Platforms (1)
GPL1261 [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
Samples (71)
GSM239868 AK_Control_ZT 0_1
GSM239869 AK_Control_ZT 0_2
GSM239870 AK_Control_ZT 0_3
This SubSeries is part of SuperSeries:
GSE9444 Sleep deprivation and the brain
BioProject PRJNA105157

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Supplementary file Size Download File type/resource
GSE9442_RAW.tar 431.1 Mb (http)(custom) TAR (of CEL)
Raw data provided as supplementary file
Processed data included within Sample table

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