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| Status |
Public on Dec 07, 2007 |
| Title |
VSartorelli SMC Calorie Restriction |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
The integration of positive and negative intra- and extra-cellular signals dictates whether a cell will proliferate or differentiate. While it is intuitive to speculate that nutrients availability may influence this alternative, a comprehensive complement of the molecular determinants involved in this process has not been elucidated yet. In this study, we will investigate how nutrients (glucose) affect skeletal myogenesis. C2C12 cells will be cultured in high glucose and low glucose conditions, and their differenciation will be studied.
Keywords: Differential Design, Differentiation Medium (DM), Growth Medium (GM)
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| |
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| Overall design |
We hypothesize that calorie restriction may have an effect on appropriate differentiation of skeletal myoblasts and this effect can be demonstrated by expression profiling.
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| |
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| Contributor(s) |
Sartorelli V |
| Citation(s) |
18477450 |
| Submission date |
Dec 03, 2007 |
| Last update date |
Oct 01, 2019 |
| Contact name |
Eric P Hoffman |
| E-mail(s) |
ericphoffman@gmail.com
|
| Organization name |
Binghamton University - SUNY
|
| Department |
Pharmaceutical Sciences
|
| Street address |
PO Box 6000
|
| City |
Binghamton |
| State/province |
NY |
| ZIP/Postal code |
13902 |
| Country |
USA |
| |
|
| Platforms (2) |
| GPL339 |
[MOE430A] Affymetrix Mouse Expression 430A Array |
| GPL340 |
[MOE430B] Affymetrix Mouse Expression 430B Array |
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| Samples (24)
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| Relations |
| BioProject |
PRJNA103685 |
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