|
| Status |
Public on May 31, 2018 |
| Title |
Next Generation Sequencing Facilitates Quantitative Analysis for H3K27ac mediated chromatin conformation capture of Wild Type and PVT1 Knockdown by CRISPRi in MDA-MB-231 human breast cancer cell line |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
CRISPRi targeting PVT1 specifically decrease PVT1-MYC interaction
|
| |
|
| Overall design |
HiChIP performed with biological replicates for CRISPRi-PVT1 with H3K27ac
|
| |
|
| Contributor(s) |
Cho SW, Chang HY |
| Citation(s) |
29731168 |
| Submission date |
Apr 10, 2017 |
| Last update date |
May 15, 2019 |
| Contact name |
Howard Y. Chang |
| E-mail(s) |
howchang@stanford.edu
|
| Phone |
650-725-7022
|
| Organization name |
Stanford
|
| Lab |
Chang Lab
|
| Street address |
269 Campus Drive, CCSR 2130
|
| City |
Stanford |
| State/province |
CALIFORNIA |
| ZIP/Postal code |
94305 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL20301 |
Illumina HiSeq 4000 (Homo sapiens) |
|
| Samples (6)
|
|
| This SubSeries is part of SuperSeries: |
| GSE97669 |
Promoter of lncRNA gene *PVT1* is a tumor suppressor DNA element |
|
| Relations |
| BioProject |
PRJNA382387 |
| SRA |
SRP103777 |
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