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| Status |
Public on Apr 11, 2019 |
| Title |
Impact of miR-199a-5p silencing on bleomycin-induced lung fibrosis |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
To assess the impact of miR-199a-5p silencing on lung fibrogenesis, LNA-miR-199a-5p (5mg/kg) or control formulated for in vivo delivery was instilled intratracheally 4 days and 2 days before intratracheal administration of bleomycin (1 unit/kg) or PBS as well as 4 days after bleomycin or PBS treatment.
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| Overall design |
Experiments were performed in a one color design, corresponding to 4 conditions (LNA-control + PBS n = 3, LNA-miR-199a-5p + PBS n = 3, LNA-control + Bleomycin n = 5, LNA-miR-199a-5p + bleomycin n = 5) for a total of 16 samples.
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| Web link |
http://www.genomique.info:8080/merge/index
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| Contributor(s) |
Savary G, Nottet N, Pottier N, Mari B, Barbry P, Lebrigand K |
| Citation(s) |
30964696 |
| Submission date |
Apr 14, 2017 |
| Last update date |
Mar 31, 2020 |
| Contact name |
Kevin Lebrigand |
| Organization name |
IPMC/CNRS
|
| Lab |
Functional Genomics Platform of Nice-Sophia-Antipolis, France.
|
| Street address |
660 route des lucioles
|
| City |
Valbonne - Sophia-Antipolis |
| ZIP/Postal code |
06560 |
| Country |
France |
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| Platforms (1) |
| GPL13912 |
Agilent-028005 SurePrint G3 Mouse GE 8x60K Microarray (Feature Number version) |
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| Samples (16)
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| This SubSeries is part of SuperSeries: |
| GSE97834 |
The DNM3OS lncRNA is a reservoir of fibromiRs with major functions in fibroblast response to TGF-beta and fibrogenesis |
|
| Relations |
| BioProject |
PRJNA382976 |
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