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| Status |
Public on Dec 12, 2007 |
| Title |
Gene expression analysis of brain cortex of olfactory-bulbectomized rats |
| Organism |
Rattus norvegicus |
| Experiment type |
Expression profiling by array
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| Summary |
Animal models represent a very useful tool for the study of depressive-like behaviour and for the evaluation of the therapeutic efficacy of antidepressants. Nevertheless, gene expression patterns of these different animal models and whether genes classically associated to human major depression are present in these genetic profiles remain unknown. Gene expression was evaluated in an animal model of depression: olfactory-bulbectomized rats. Gene expression analyses were carried out using the Affymetrix® GeneChip® technology.
Keywords: Bulbectomized vs sham-operated comparative genomics study
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| Overall design |
In total, 11 animals were studied, five bulbectomized rats and six sham-operated rats
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| Contributor(s) |
Uriguen L, Arteta D, Diez-Alarcia R, Ferrer-Alcon M, Diaz A, Pazos A, Meana J |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Dec 05, 2007 |
| Last update date |
Jul 31, 2017 |
| Contact name |
Leyre Uriguen |
| E-mail(s) |
leyre.uriguen@ehu.es
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| Phone |
+34946015674
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| Fax |
+34946013220
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| Organization name |
University of the Basque Country
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| Department |
Pharmacology
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| Street address |
Barrio Sarriena s/n
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| City |
Leioa |
| State/province |
Vizcaya |
| ZIP/Postal code |
48940 |
| Country |
Spain |
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| Platforms (1) |
| GPL1355 |
[Rat230_2] Affymetrix Rat Genome 230 2.0 Array |
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| Samples (11)
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| This SubSeries is part of SuperSeries: |
| GSE9798 |
Gene expression analysis of brain cortex |
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| Relations |
| BioProject |
PRJNA105117 |
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