|
| Status |
Public on May 11, 2017 |
| Title |
RNAseq analysis of murine brainstem gliomas with and without H3.3K27M |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Using the RCAS/tv-a system, we induced murine brainstem gliomas (PDGF-B; p53 loss using RCAS-Cre with and without H3.3K27M) in Nestin tv-a; p53 floxed mice
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| |
|
| Overall design |
Three independent tumors with H3.3K27M (PKC) and three independent tumors without H3.3K27M (PDC) were snap frozen, RNA extracted, and RNAseq analysis was performed (PDGF-B; H3.3K27M; p53 loss vs. PDGF-B; p53 loss)
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| |
|
| Contributor(s) |
Becher O, Cordero F |
| Citation(s) |
28522693 |
| Submission date |
May 10, 2017 |
| Last update date |
May 15, 2019 |
| Contact name |
Oren Josh Becher |
| E-mail(s) |
oren.becher@mssm.edu
|
| Phone |
212-241-7605
|
| Organization name |
Mount Sinai
|
| Department |
Pediatrics
|
| Lab |
Becher Lab
|
| Street address |
1468 Madison Avenue, A21-02
|
| City |
New York |
| State/province |
NY |
| ZIP/Postal code |
10029 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL9185 |
Illumina Genome Analyzer (Mus musculus) |
|
| Samples (6)
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|
| Relations |
| BioProject |
PRJNA386160 |
| SRA |
SRP106786 |
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