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Series GSE99555 Query DataSets for GSE99555
Status Public on Sep 06, 2017
Title Expression data from lung metastasis
Organism Mus musculus
Experiment type Expression profiling by array
Summary The role of PGC1alpha in breast cancer lung metastasis is largely unknown. We used expression data from lung metastasis of mice injected with PGC1alpha overexpression or control cells to understand global changes that occur upon overexpression of PGC1alpha that lead to lung metastasis.
We used expression data to understand the pathways and genes that may lead to lung metastasis in a PGC1alpha overexpression setting.
Overall design Mice were injected by tail vein with either PGC1alpha overexpressing or control cells (NMuMG-ErbB2/PGC-1alpha and NMuMG-ErbB2/VC cells ) respectively. Mice were treated with phenformin for 1 week or PBS control. Lung metastasis was isolated by laser capture microdissection.
Contributor(s) Andrzjewski S, Johnson RM, Tabari├Ęs S, Annis MG
Citation(s) 28988825
Submission date Jun 01, 2017
Last update date Jul 25, 2021
Contact name Julie St-Pierre
Organization name McGill University
Department Department of Biochemistry
Street address 3655 Promenade Sir William Osler
City Montreal
State/province Quebec
ZIP/Postal code H3G 1Y6
Country Canada
Platforms (1)
GPL23038 [Clariom_S_Mouse] Affymetrix Clariom S Assay, Mouse (Includes Pico Assay)
Samples (22)
GSM2645893 NMuMG-ErbB2/PGC-1alpha_Phenformin1
GSM2645894 NMuMG-ErbB2/PGC-1alpha_Phenformin2
GSM2645895 NMuMG-ErbB2/PGC-1alpha_Phenformin3
This SubSeries is part of SuperSeries:
GSE99557 Expression data from a lung metastatic cell line or metastatic explants in mouse and human
BioProject PRJNA388964

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE99555_RAW.tar 24.5 Mb (http)(custom) TAR (of CEL)
GSE99555_normalized_data_allcontrols.txt.gz 3.5 Mb (ftp)(http) TXT
Raw data provided as supplementary file
Processed data included within Sample table
Processed data are available on Series record

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