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Series GSE99556 Query DataSets for GSE99556
Status Public on Sep 06, 2017
Title Expression data from lung metastatic explants
Organism Mus musculus
Experiment type Expression profiling by array
Summary The role of PGC1alpha in breast cancer lung metastasis is largely unknown. We used expression data from lung metastatic explants overexpressing PGC1alpha or control, treated with phenformin to understand global gene expression changes which occur in a PGC1alpha context and under phenformin treatment.
We used expression data to understand the pathways and genes that may lead to lung metastasis in a PGC1alpha overexpression setting.
Overall design PGC1alpha overexpressing or control explants from a lung metastatic tail vein (LMTV) assay were isolated and put into culture and treated with phenformin (100uM) for 4 days or dh20 control.
Contributor(s) Andrzjewski S, Johnson RM, Tabari├Ęs S, Annis MG
Citation(s) 28988825
Submission date Jun 01, 2017
Last update date Jul 25, 2021
Contact name Julie St-Pierre
Organization name McGill University
Department Department of Biochemistry
Street address 3655 Promenade Sir William Osler
City Montreal
State/province Quebec
ZIP/Postal code H3G 1Y6
Country Canada
Platforms (1)
GPL23038 [Clariom_S_Mouse] Affymetrix Clariom S Assay, Mouse (Includes Pico Assay)
Samples (12)
GSM2645915 LMTV_NMuMG-ErbB2/PGC-1alpha_ctrl_1
GSM2645916 LMTV_NMuMG-ErbB2/PGC-1alpha_ctrl_2
GSM2645917 LMTV_NMuMG-ErbB2/PGC-1alpha_ctrl_3
This SubSeries is part of SuperSeries:
GSE99557 Expression data from a lung metastatic cell line or metastatic explants in mouse and human
BioProject PRJNA388965

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE99556_RAW.tar 13.7 Mb (http)(custom) TAR (of CEL)
GSE99556_normalized_data_allcontrols.txt.gz 2.0 Mb (ftp)(http) TXT
Raw data provided as supplementary file
Processed data included within Sample table
Processed data are available on Series record

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