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Sample GSM1441434 Query DataSets for GSM1441434
Status Public on Jul 23, 2014
Title MiR-21 knockout replicate 1
Sample type RNA
 
Source name MiR-21-KO
Organism Mus musculus
Characteristics tissue: colon mucosa
strain: c57BL/6
genotype: MiR-21 knockout
group: MiR-21-KO
Treatment protocol MiR-21-/- (21KO) mice on C57BL/6 background were kindly provided by Dr. Eric Olson (Patrick, et al. J Clin Invest. 2010;120:3912-3916.). The miR-21-/- mice do not develop spontaneous colitis. Gene expression profiles were established for normal miR-21-/- mice and wild type c57BL/6 mice (WT) from Taconic Farm Inc. (Hudson, NY)
Extracted molecule total RNA
Extraction protocol Trizol extraction of total RNA was performed according to the manufacturer's instructions.
Label Cy3
Label protocol not provided
 
Hybridization protocol Hybridized to Illumina MouseRef-8 v2.0 expression beadchip.
Scan protocol not provided
Description JK5
Data processing raw data were processed using the R/Bioconductor package limma for background correction and quantile normalization
 
Submission date Jul 22, 2014
Last update date Jul 23, 2014
Contact name Yong Huang
E-mail(s) yh9fj@virginia.edu
Phone (434) 243-0842
Organization name University of Viginia
Department Medicine
Street address 1340 Jefferson Park Ave
City Charlottesville
State/province VA
ZIP/Postal code 22908
Country USA
 
Platform ID GPL6885
Series (2)
GSE59648 Divergent influence of microRNA-21 deletion on murine colitis phenotypes [mRNA]
GSE59651 Divergent influence of microRNA-21 deletion on murine colitis phenotypes

Data table header descriptions
ID_REF
VALUE background-corrected, quantile-normalized and log2-transformed

Data table
ID_REF VALUE
ILMN_1212607 4.246188064
ILMN_1212612 4.989645922
ILMN_1212619 4.637214846
ILMN_1212632 4.7785734
ILMN_1212636 9.96137514
ILMN_1212637 7.993566695
ILMN_1212645 4.565557257
ILMN_1212648 5.983671523
ILMN_1212653 6.148382097
ILMN_1212672 5.644172951
ILMN_1212682 4.327767296
ILMN_1212692 9.628306056
ILMN_1212693 5.737375243
ILMN_1212695 4.241232656
ILMN_1212702 9.643830905
ILMN_1212703 7.349240126
ILMN_1212717 4.985113054
ILMN_1212720 5.196427667
ILMN_1212759 6.56954774
ILMN_1212791 4.837587568

Total number of rows: 18010

Table truncated, full table size 437 Kbytes.




Supplementary data files not provided
Processed data included within Sample table

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