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Status
Public on Apr 10, 2007
Title
19 saline
Sample type
RNA
Source name
male sprague-dawley rat, 21 days saline
Organism
Rattus norvegicus
Extracted molecule
total RNA
Description
Male Sprague-Dawley albino rats (Charles River) initially weighting approximately 200 grams were randomly assigned to one of the following: 1) olanzapine (2 mg/kg/day, I.P.) (N=20) or 2) Saline (N=20) and administered olanzapine or saline for 21 days. Frontal cortex (N=4/group) was dissected and homogenized for microarray, QPCR and western blotting following previous methods (Fatemi et al. 2003; Brooks et al. 2003). RNA isolation, cDNA preparation, microarray hybridization and QPCR followed previous methods (Brooks et al. 2003). Keywords = olanzapine Keywords = frontal cortex
Submission date
Apr 20, 2005
Last update date
Apr 10, 2006
Contact name
S. Hossein Fatemi
E-mail(s)
fatem002@umn.edu
Phone
612-626-3633
Fax
612-624-8935
Organization name
University of Minnesota
Department
Department of Psychiatry, Division of Neuroscience Research
Street address
420 Delaware St SE, MMC 392
City
Minneapolis
State/province
MN
ZIP/Postal code
55455
Country
USA
Platform ID
GPL1355
Series (1)
GSE2547
Olanzapine vs. Saline rat pfc
Data table header descriptions
ID_REF
VALUE
RMA
ABS_CALL
Detection
DETECTION P-VALUE
Detection p-value
Data table
ID_REF
VALUE
ABS_CALL
DETECTION P-VALUE
AFFX-BioB-5_at
1402.3237
P
5.17E-05
AFFX-BioB-M_at
1923.7405
P
5.17E-05
AFFX-BioB-3_at
1811.6669
P
2.97E-04
AFFX-BioC-5_at
4203.4556
P
4.43E-05
AFFX-BioC-3_at
2336.3652
P
4.43E-05
AFFX-BioDn-5_at
7176.0356
P
4.43E-05
AFFX-BioDn-3_at
15975.437
P
4.43E-05
AFFX-CreX-5_at
27742.928
P
5.17E-05
AFFX-CreX-3_at
28412.666
P
4.43E-05
AFFX-DapX-5_at
5.5588193
A
0.8910214
AFFX-DapX-M_at
13.113255
A
0.8605175
AFFX-DapX-3_at
7.603967
A
0.973889
AFFX-LysX-5_at
15.989908
A
0.44064635
AFFX-LysX-M_at
18.614183
A
0.5886198
AFFX-LysX-3_at
4.8714204
A
0.8978349
AFFX-PheX-5_at
24.77715
A
0.4702405
AFFX-PheX-M_at
6.2760606
A
0.9219982
AFFX-PheX-3_at
12.9866905
A
0.82467175
AFFX-ThrX-5_at
64.340355
A
0.20573238
AFFX-ThrX-M_at
22.61153
A
0.8910214
Total number of rows: 31099 Table truncated, full table size 974 Kbytes .Supplementary data files not provided