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Status
Public on Apr 10, 2007
Title
9 olanzapine
Sample type
RNA
Source name
male sprague-dawley rat, 21 days olanzapine
Organism
Rattus norvegicus
Extracted molecule
total RNA
Description
Male Sprague-Dawley albino rats (Charles River) initially weighting approximately 200 grams were randomly assigned to one of the following: 1) olanzapine (2 mg/kg/day, I.P.) (N=20) or 2) Saline (N=20) and administered olanzapine or saline for 21 days. Frontal cortex (N=4/group) was dissected and homogenized for microarray, QPCR and western blotting following previous methods (Fatemi et al. 2003; Brooks et al. 2003). RNA isolation, cDNA preparation, microarray hybridization and QPCR followed previous methods (Brooks et al. 2003). Keywords = olanzapine Keywords = frontal cortex
Submission date
Apr 20, 2005
Last update date
Apr 10, 2006
Contact name
S. Hossein Fatemi
E-mail(s)
fatem002@umn.edu
Phone
612-626-3633
Fax
612-624-8935
Organization name
University of Minnesota
Department
Department of Psychiatry, Division of Neuroscience Research
Street address
420 Delaware St SE, MMC 392
City
Minneapolis
State/province
MN
ZIP/Postal code
55455
Country
USA
Platform ID
GPL1355
Series (1)
GSE2547
Olanzapine vs. Saline rat pfc
Data table header descriptions
ID_REF
VALUE
RMA
ABS_CALL
detection
DETECTION P-VALUE
detection p-value
Data table
ID_REF
VALUE
ABS_CALL
DETECTION P-VALUE
AFFX-BioB-5_at
1569.3944
P
5.17E-05
AFFX-BioB-M_at
2475.7058
P
5.17E-05
AFFX-BioB-3_at
1854.3192
P
8.14E-05
AFFX-BioC-5_at
4726.692
P
4.43E-05
AFFX-BioC-3_at
2569.592
P
4.43E-05
AFFX-BioDn-5_at
8267.944
P
4.43E-05
AFFX-BioDn-3_at
16750.852
P
4.43E-05
AFFX-CreX-5_at
28019.08
P
5.17E-05
AFFX-CreX-3_at
29803.146
P
4.43E-05
AFFX-DapX-5_at
10.012152
A
0.7834759
AFFX-DapX-M_at
10.059314
A
0.94977105
AFFX-DapX-3_at
8.451587
A
0.9370707
AFFX-LysX-5_at
13.460952
A
0.4113802
AFFX-LysX-M_at
40.029987
A
0.4554125
AFFX-LysX-3_at
53.775425
A
0.35445267
AFFX-PheX-5_at
17.981924
A
0.57403773
AFFX-PheX-M_at
10.880121
A
0.65933883
AFFX-PheX-3_at
18.454695
A
0.65933883
AFFX-ThrX-5_at
8.61354
A
0.8605175
AFFX-ThrX-M_at
17.352766
A
0.8047336
Total number of rows: 31099 Table truncated, full table size 973 Kbytes .Supplementary data files not provided