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Sample GSM80024 Query DataSets for GSM80024
Status Public on Oct 27, 2005
Title 26611, GATA2 non-overexpresed, FLT3 non-mutated
Sample type RNA
 
Channel 1
Source name AML-M1 leukemia patient 26611, GATA2 non-overexpresed, FLT3 non-mutated
Organism Homo sapiens
Characteristics Bone marrow of patient with AML-M1, history number 26611. Without GATA2 overexpression nor FLT3 ITD mutation
Extracted molecule total RNA
Label cy5
 
Channel 2
Source name Pool 9 healthy bone marrows
Organism Homo sapiens
Characteristics Pool of 9 healthy bone marrows
Extracted molecule total RNA
Label cy3
 
 
Description Expression profiling of the leukemia patient number 26611, not presenting GATA overexpression nor FLT3 mutation.
Data processing Data were imported to the Array Norm 1.7.2 software (Institute for Genomics and Bioinformatics, Graz University of Technology, Austria) for data processing and normalization. The intensity value associated to each spot was calculated subtracting the local background noise from the foreground values. Then, the Lowess normalization method was applied to normalize the data. Finally, the scale across slides function was used and the data were base 2 logarithm transformed and imported to the Genesis software (Institute for Genomics and Bioinformatics, Graz University of Technology, Austria) for statistical analysis. Only genes without missing values were included in the analysis. All different comparisons between groups were performed by using ANOVA with a p value threshold of 0.01 and a fold ratio threshold of 2 between the two groups of patients tested in each comparison.
 
Submission date Oct 25, 2005
Last update date Oct 26, 2005
Contact name Raquel Malumbres
E-mail(s) rmalumbres@yahoo.com
Phone +34 948194700
Organization name University of Navarra/ ClĂ­nica Universidad de Navarra
Department Hemato-Oncology
Lab Multiple Myeloma
Street address Avenida Pio XII 55
City Pamplona
State/province Navarra
ZIP/Postal code 31008
Country Spain
 
Platform ID GPL2006
Series (1)
GSE3505 Mutational state FLT3-ITD and GATA2 overexpression could define a subgroup of AML-M1 patients with normal karyotype

Data table header descriptions
ID_REF
VALUE Normalized log ratio (Lowess normalization)
CH1_SIG_MEAN Signal intensity value of the patient sample
CH1_BKD_MEAN Background intensity value of the patient sample
CH2_SIG_MEAN Signal intensity value of the bone marrow pool sample
CH2_BKD_MEAN Background intensity value of the bone marrow pool sample

Data table
ID_REF VALUE CH1_SIG_MEAN CH1_BKD_MEAN CH2_SIG_MEAN CH2_BKD_MEAN
1 0.40422502 1075.180723 161.6178344 529.1566265 225.5286624
2 1.3736178 1345.831325 172.7515924 482.6506024 246.5732484
3 1.0807025 3685.542169 177.1082803 1083.759036 246.0127389
4 2.635064 5071.060241 163.8057143 733.1325301 233.28
5 1.1360048 1840.120482 159.8981481 618.6506024 246.9166667
6 2.4854856 2895.39759 177.910828 557.1325301 257.3503185
7 1.1194619 868.8674699 157.6178344 402.8915663 223.566879
8 1.8775976 1492.60241 169.2457143 447.6626506 242.4342857
9 1.6945957 1445.421687 194.7542857 466.1445783 252.8228571
10 0.65855765 867.4939759 163.8980892 457.4457831 237.9745223
11 2745.879518 180.6369427 552.5301205 258.2802548
12 3.576033 4700.722892 184.3085714 531.3253012 258.3657143
13 3.4657848 6898.53012 197.2352941 721.253012 252.4264706
14 1.292315 1359.662651 188.4840764 499.2289157 253.4394904
15 3.4322546 3846.915663 182.0382166 491.3975904 243.9490446
16 2.151025 3170.120482 190.4713376 645.2289157 267.7834395
17 2.859902 3915.39759 190.5350318 604.6024096 278.3694268
18 1.4603741 3104.096386 179.3248408 816.0963855 294.6878981
19 1.9354792 3622.26506 196.7179487 774.1927711 295.9179487
20 2.1393073 2683.325301 181.4140127 625.1325301 294.6624204

Total number of rows: 19200

Table truncated, full table size 1174 Kbytes.




Supplementary file Size Download File type/resource
GSM80024-cy3.txt.gz 966.0 Kb (ftp)(http) TXT
GSM80024-cy5.txt.gz 980.5 Kb (ftp)(http) TXT

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