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    1190005I06Rik RIKEN cDNA 1190005I06 gene [ Mus musculus (house mouse) ]

    Gene ID: 68918, updated on 5-Mar-2024

    Summary

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    Official Symbol
    1190005I06Rikprovided by MGI
    Official Full Name
    RIKEN cDNA 1190005I06 geneprovided by MGI
    Primary source
    MGI:MGI:1916168
    See related
    Ensembl:ENSMUSG00000043687 AllianceGenome:MGI:1916168
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Is expressed in Meckel's cartilage; nervous system; neural retina; and skeleton. Orthologous to human C16orf74 (chromosome 16 open reading frame 74). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in adrenal adult (RPKM 10.5), mammary gland adult (RPKM 8.5) and 25 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See 1190005I06Rik in Genome Data Viewer
    Location:
    8 E1; 8 69.92 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (121335341..121361129, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (120608602..120634390, complement)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene genetic suppressor element 1, coiled-coil protein Neighboring gene STARR-positive B cell enhancer ABC_E246 Neighboring gene predicted gene 10614 Neighboring gene GINS complex subunit 2 Neighboring gene STARR-seq mESC enhancer starr_22909 Neighboring gene predicted gene, 27021 Neighboring gene predicted gene, 33075 Neighboring gene cytochrome c oxidase subunit 4I1 Neighboring gene ER membrane protein complex subunit 8

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Genomic analysis of mouse retinal development. Blackshaw S, et al. PLoS Biol, 2004 Sep. PMID 15226823, Free PMC Article
    2. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808
    3. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
    4. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
    5. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Potential readthrough

    Included gene: Emc8

    Readthrough Gm27021

    Readthrough gene: Gm27021, Included gene: Emc8

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein C16orf74 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_197988.3 → NP_932105.2  uncharacterized protein C16orf74 homolog

      Status: VALIDATED

      Source sequence(s)
      BC027666, CX237485
      Consensus CDS
      CCDS52690.1
      UniProtKB/Swiss-Prot
      E9PUE0, Q8K1L6
      Related
      ENSMUSP00000119467.2, ENSMUST00000123927.9
      Conserved Domains (1) summary
      pfam15366
      Location:48 → 110
      DUF4597; Domain of unknown function (DUF4597)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      121335341..121361129 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8K1L6.3 GenPept UniProtKB/Swiss-Prot:Q8K1L6

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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