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    Sec22c SEC22 homolog C, vesicle trafficking protein [ Rattus norvegicus (Norway rat) ]

    Gene ID: 687022, updated on 6-Jun-2024

    Summary

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    Official Symbol
    Sec22cprovided by RGD
    Official Full Name
    SEC22 homolog C, vesicle trafficking proteinprovided by RGD
    Primary source
    RGD:1590146
    See related
    Ensembl:ENSRNOG00000047873 AllianceGenome:RGD:1590146
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport. Predicted to be located in endoplasmic reticulum membrane. Predicted to be integral component of membrane. Orthologous to human SEC22C (SEC22 homolog C, vesicle trafficking protein). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Brain (RPKM 60.2), Thymus (RPKM 51.3) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Sec22c in Genome Data Viewer
    Location:
    8q32
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (130223349..130249079, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (121345839..121371509, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (130319682..130345774, complement)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120094302 Neighboring gene vasoactive intestinal peptide receptor 1 Neighboring gene SS18 like 2 Neighboring gene natural killer cell triggering receptor

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    vesicle-trafficking protein SEC22c
    Names
    SEC22 vesicle trafficking protein homolog C

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001427607.2 → NP_001414536.1  vesicle-trafficking protein SEC22c

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000008
      UniProtKB/TrEMBL
      A6I449, M0R3S2

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      130223349..130249079 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039082762.2 → XP_038938690.1  vesicle-trafficking protein SEC22c isoform X1

      Conserved Domains (1) summary
      cd14824
      Location:5 → 123
      Longin; longin domain

    2. XM_063266150.1 → XP_063122220.1  vesicle-trafficking protein SEC22c isoform X2

      UniProtKB/TrEMBL
      A6I449, M0R3S2

    3. XM_063266151.1 → XP_063122221.1  vesicle-trafficking protein SEC22c isoform X2

      UniProtKB/TrEMBL
      A6I449, M0R3S2

    4. XM_039082761.2 → XP_038938689.1  vesicle-trafficking protein SEC22c isoform X1

      Conserved Domains (1) summary
      cd14824
      Location:5 → 123
      Longin; longin domain

    5. XM_039082760.2 → XP_038938688.1  vesicle-trafficking protein SEC22c isoform X1

      Conserved Domains (1) summary
      cd14824
      Location:5 → 123
      Longin; longin domain

    6. XM_039082767.2 → XP_038938695.1  vesicle-trafficking protein SEC22c isoform X5

    7. XM_039082768.2 → XP_038938696.1  vesicle-trafficking protein SEC22c isoform X6

    8. XM_063266153.1 → XP_063122223.1  vesicle-trafficking protein SEC22c isoform X7

    9. XM_039082765.2 → XP_038938693.1  vesicle-trafficking protein SEC22c isoform X3

      Conserved Domains (1) summary
      pfam13774
      Location:6 → 68
      Longin; Regulated-SNARE-like domain

    10. XM_039082766.1 → XP_038938694.1  vesicle-trafficking protein SEC22c isoform X4

      Conserved Domains (1) summary
      cd14824
      Location:5 → 123
      Longin; longin domain
    Nucleotide Protein Strain
    Heading Accession and Version

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