Tada1 transcriptional adaptor 1 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Tada1provided by RGD
Official Full Name: transcriptional adaptor 1provided by RGD
Primary source: RGD:1306774
See related: Ensembl:ENSRNOG00000003816 AllianceGenome:RGD:1306774
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Tada1l; RGD1306774
Summary: Predicted to enable transcription coactivator activity. Predicted to be involved in histone H3 acetylation and regulation of transcription by RNA polymerase II. Predicted to be located in cytosol; focal adhesion; and nucleoplasm. Predicted to be part of SAGA complex. Orthologous to human TADA1 (transcriptional adaptor 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Thymus (RPKM 117.9), Lung (RPKM 100.5) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 13q23

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	13	NC_086031.1 (81165871..81180421)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	13	NC_051348.1 (78632908..78646863)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	13	NC_005112.4 (84588587..84602542)

Chromosome 13 - NC_086031.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

RH138100 (e-PCR)
- UniSTS:220187

D3S2967E (e-PCR)
- UniSTS:150951

RH136996 (e-PCR)
- UniSTS:219085

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables transcription coactivator activity	IBA Inferred from Biological aspect of Ancestor more info
enables transcription coactivator activity	IEA Inferred from Electronic Annotation more info
enables transcription coactivator activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info
involved_in positive regulation of DNA-templated transcription	IEA Inferred from Electronic Annotation more info
involved_in regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of SAGA complex	IBA Inferred from Biological aspect of Ancestor more info
part_of SAGA complex	IEA Inferred from Electronic Annotation more info
part_of SAGA complex	ISO Inferred from Sequence Orthology more info
located_in cytosol	IEA Inferred from Electronic Annotation more info
located_in cytosol	ISO Inferred from Sequence Orthology more info
located_in focal adhesion	IEA Inferred from Electronic Annotation more info
located_in focal adhesion	ISO Inferred from Sequence Orthology more info
located_in nucleoplasm	IEA Inferred from Electronic Annotation more info
located_in nucleoplasm	ISO Inferred from Sequence Orthology more info
located_in nucleus	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: transcriptional adapter 1

Names: transcriptional adapter 1-like protein; transcriptional adaptor 1 (HFI1 homolog, yeast) like; transcriptional adaptor 1- like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001037980.2 → NP_001033069.2 transcriptional adapter 1

See identical proteins and their annotated locations for NP_001033069.2

Status: PROVISIONAL

Source sequence(s)

BC158713

UniProtKB/Swiss-Prot

Q5BJQ7

UniProtKB/TrEMBL

A0A0H2UHC2, B0BN76

Related

ENSRNOP00000005090.6, ENSRNOT00000005090.8

Conserved Domains (1) summary

pfam12767
Location:7 → 193

SAGA-Tad1; Transcriptional regulator of RNA polII, SAGA, subunit

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086031.1 Reference GRCr8

Range

81165871..81180421

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_039090914.2 → XP_038946842.1 transcriptional adapter 1 isoform X1

Conserved Domains (1) summary

pfam12767
Location:51 → 106

SAGA-Tad1; Transcriptional regulator of RNA polII, SAGA, subunit