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    Faiml Fas apoptotic inhibitory molecule like [ Mus musculus (house mouse) ]

    Gene ID: 623459, updated on 8-Feb-2024

    Summary

    Official Symbol
    Faimlprovided by MGI
    Official Full Name
    Fas apoptotic inhibitory molecule likeprovided by MGI
    Primary source
    MGI:MGI:3647754
    See related
    Ensembl:ENSMUSG00000096316 AllianceGenome:MGI:3647754
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm6432; EG623459
    Summary
    Predicted to be involved in I-kappaB kinase/NF-kappaB signaling; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors; and positive regulation of neurogenesis. Orthologous to human FAIM (Fas apoptotic inhibitory molecule). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Restricted expression toward testis adult (RPKM 5.8) See more
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    Genomic context

    See Faiml in Genome Data Viewer
    Location:
    9 E3.3; 9 51.44 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (99111429..99119292, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (99229376..99237239, complement)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 33857 Neighboring gene centrosomal protein 70 Neighboring gene predicted gene 2950 Neighboring gene STARR-positive B cell enhancer ABC_E9773 Neighboring gene STARR-seq mESC enhancer starr_25018 Neighboring gene DnaJ (Hsp40) homolog, subfamily C, member 8 pseudogene Neighboring gene RIKEN cDNA 4930422M22 gene Neighboring gene DnaJ (Hsp40) homolog, subfamily C, member 14 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in negative regulation of extrinsic apoptotic signaling pathway via death domain receptors IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
     

    General protein information

    Preferred Names
    fas apoptotic inhibitory molecule 1-like

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001244762.1NP_001231691.1  fas apoptotic inhibitory molecule 1-like

      See identical proteins and their annotated locations for NP_001231691.1

      Status: VALIDATED

      Source sequence(s)
      AC159899
      Consensus CDS
      CCDS57691.1
      UniProtKB/TrEMBL
      J3QPY3
      Related
      ENSMUSP00000137541.2, ENSMUST00000178051.8
      Conserved Domains (1) summary
      pfam06905
      Location:3173
      FAIM1; Fas apoptotic inhibitory molecule (FAIM1)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      99111429..99119292 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)