Pop1 POP1 homolog, ribonuclease P/MRP subunit [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Pop1provided by RGD
Official Full Name: POP1 homolog, ribonuclease P/MRP subunitprovided by RGD
Primary source: RGD:1308609
See related: Ensembl:ENSRNOG00000005243 AllianceGenome:RGD:1308609
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable ribonuclease P RNA binding activity. Predicted to contribute to ribonuclease P activity. Predicted to be involved in RNA phosphodiester bond hydrolysis, endonucleolytic; tRNA 5'-leader removal; and tRNA catabolic process. Predicted to be located in nucleolus. Predicted to be part of nucleolar ribonuclease P complex and ribonuclease MRP complex. Human ortholog(s) of this gene implicated in anauxetic dysplasia 2. Orthologous to human POP1 (POP1 homolog, ribonuclease P/MRP subunit). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Kidney (RPKM 44.9), Thymus (RPKM 25.7) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 7q22

Exon count:: 17

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	7	NC_086025.1 (67590502..67618187)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	7	NC_051342.1 (65705348..65733143)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	7	NC_005106.4 (73270403..73298209)

Chromosome 7 - NC_086025.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

D7Rat165 (e-PCR), detects polymorphism
- UniSTS:228116

BE105841 (e-PCR)
- UniSTS:245918

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables ribonuclease P RNA binding	ISO Inferred from Sequence Orthology more info
contributes_to ribonuclease P activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info
involved_in tRNA 5'-leader removal	ISO Inferred from Sequence Orthology more info
involved_in tRNA decay	ISO Inferred from Sequence Orthology more info
involved_in tRNA processing	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of multimeric ribonuclease P complex	ISO Inferred from Sequence Orthology more info
part_of nucleolar ribonuclease P complex	IBA Inferred from Biological aspect of Ancestor more info
part_of nucleolar ribonuclease P complex	ISO Inferred from Sequence Orthology more info
located_in nucleolus	ISO Inferred from Sequence Orthology more info
part_of ribonuclease MRP complex	IBA Inferred from Biological aspect of Ancestor more info
part_of ribonuclease MRP complex	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: ribonucleases P/MRP protein subunit POP1

Names: processing of precursor 1, ribonuclease P/MRP subunit

NP_001124022.1

EC 3.1.26.5

XP_006241605.1

EC 3.1.26.5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.