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    Tapt1 transmembrane anterior posterior transformation 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 305386, updated on 11-Apr-2024

    Summary

    Official Symbol
    Tapt1provided by RGD
    Official Full Name
    transmembrane anterior posterior transformation 1provided by RGD
    Primary source
    RGD:1309656
    See related
    Ensembl:ENSRNOG00000003174 AllianceGenome:RGD:1309656
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1309656
    Summary
    Predicted to be involved in maintenance of protein localization in endoplasmic reticulum and positive regulation of cilium assembly. Predicted to act upstream of or within embryonic skeletal system development. Predicted to be located in centrosome. Predicted to be active in ciliary basal body. Predicted to be integral component of endoplasmic reticulum membrane. Orthologous to human TAPT1 (transmembrane anterior posterior transformation 1). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Thymus (RPKM 336.1), Muscle (RPKM 264.1) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Tapt1 in Genome Data Viewer
    Location:
    14q21
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 14 NC_086032.1 (71085966..71132228)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 14 NC_051349.1 (66873467..66919737)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 14 NC_005113.4 (71416153..71462646)

    Chromosome 14 - NC_086032.1Genomic Context describing neighboring genes Neighboring gene Rac family small GTPase 1 like Neighboring gene uncharacterized LOC120096622 Neighboring gene uncharacterized LOC120096623 Neighboring gene U7 small nuclear RNA Neighboring gene prominin 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in cartilage development IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within embryonic skeletal system development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in ossification IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of cilium assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in positive regulation of cilium assembly ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in ciliary basal body IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in ciliary basal body ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    transmembrane anterior posterior transformation protein 1 homolog

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086032.1 Reference GRCr8

      Range
      71085966..71132228
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039092783.2XP_038948711.1  transmembrane anterior posterior transformation protein 1 homolog isoform X1

      UniProtKB/TrEMBL
      A0A8I6A632, D4A533
      Related
      ENSRNOP00000087570.1
      Conserved Domains (1) summary
      pfam05346
      Location:152456
      DUF747; Eukaryotic membrane protein family
    2. XM_039092784.2XP_038948712.1  transmembrane anterior posterior transformation protein 1 homolog isoform X2

      Conserved Domains (1) summary
      pfam05346
      Location:16320
      DUF747; Eukaryotic membrane protein family