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    Smco4 single-pass membrane protein with coiled-coil domains 4 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 363020, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Smco4provided by RGD
    Official Full Name
    single-pass membrane protein with coiled-coil domains 4provided by RGD
    Primary source
    RGD:1309410
    See related
    Ensembl:ENSRNOG00000011162 AllianceGenome:RGD:1309410
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1309410
    Summary
    Predicted to be integral component of membrane. Orthologous to human SMCO4 (single-pass membrane protein with coiled-coil domains 4). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Adrenal (RPKM 120.3), Kidney (RPKM 114.7) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Smco4 in Genome Data Viewer
    Location:
    8q12
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (20594633..20646916)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (12313235..12365534)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (14026637..14079977)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA U2-19 Neighboring gene centrosomal protein 295 Neighboring gene V-type proton ATPase subunit G 1 pseudogene Neighboring gene uncharacterized LOC134479995 Neighboring gene deuterosome assembly protein 1 Neighboring gene uncharacterized LOC134479996 Neighboring gene solute carrier family 36 member 4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    single-pass membrane and coiled-coil domain-containing protein 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001134584.1 → NP_001128056.1  single-pass membrane and coiled-coil domain-containing protein 4

      See identical proteins and their annotated locations for NP_001128056.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473993
      UniProtKB/TrEMBL
      A6JND3, D4A7S6
      Related
      ENSRNOP00000014827.4, ENSRNOT00000014827.6
      Conserved Domains (1) summary
      pfam15012
      Location:85 → 139
      DUF4519; Domain of unknown function (DUF4519)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      20594633..20646916
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017595724.3 → XP_017451213.1  single-pass membrane and coiled-coil domain-containing protein 4 isoform X2

      Conserved Domains (1) summary
      pfam15012
      Location:1 → 55
      DUF4519; Domain of unknown function (DUF4519)

    2. XM_063265724.1 → XP_063121794.1  single-pass membrane and coiled-coil domain-containing protein 4 isoform X2

    3. XM_039081705.2 → XP_038937633.1  single-pass membrane and coiled-coil domain-containing protein 4 isoform X2

      Conserved Domains (1) summary
      pfam15012
      Location:1 → 55
      DUF4519; Domain of unknown function (DUF4519)

    4. XM_039081708.2 → XP_038937636.1  single-pass membrane and coiled-coil domain-containing protein 4 isoform X2

      Conserved Domains (1) summary
      pfam15012
      Location:1 → 55
      DUF4519; Domain of unknown function (DUF4519)

    5. XM_039081707.2 → XP_038937635.1  single-pass membrane and coiled-coil domain-containing protein 4 isoform X2

      Conserved Domains (1) summary
      pfam15012
      Location:1 → 55
      DUF4519; Domain of unknown function (DUF4519)

    6. XM_039081704.2 → XP_038937632.1  single-pass membrane and coiled-coil domain-containing protein 4 isoform X1

      Conserved Domains (1) summary
      pfam15012
      Location:127 → 181
      DUF4519; Domain of unknown function (DUF4519)
    Nucleotide Protein Strain
    Heading Accession and Version

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