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    Llph LLP homolog, long-term synaptic facilitation factor [ Rattus norvegicus (Norway rat) ]

    Gene ID: 299818, updated on 5-Mar-2024

    Summary

    Official Symbol
    Llphprovided by RGD
    Official Full Name
    LLP homolog, long-term synaptic facilitation factorprovided by RGD
    Primary source
    RGD:1308261
    See related
    Ensembl:ENSRNOG00000004316 AllianceGenome:RGD:1308261
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1308261
    Summary
    Predicted to enable basal RNA polymerase II transcription machinery binding activity. Predicted to be involved in dendrite extension and positive regulation of dendritic spine development. Predicted to be located in chromosome. Predicted to be active in nucleolus. Orthologous to human LLPH (LLP homolog, long-term synaptic facilitation factor). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Thymus (RPKM 164.6), Muscle (RPKM 130.7) and 9 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Llph in Genome Data Viewer
    Location:
    7q22
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (57620925..57625924)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (55735317..55740341)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (65004544..65009509)

    Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene interleukin-1 receptor-associated kinase 3 Neighboring gene transmembrane BAX inhibitor motif containing 4 Neighboring gene high mobility group AT-hook 2 Neighboring gene uncharacterized LOC120093613 Neighboring gene uncharacterized LOC102549309

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables basal RNA polymerase II transcription machinery binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables basal RNA polymerase II transcription machinery binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in dendrite extension IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in dendrite extension ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of dendritic spine development ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in chromosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in chromosome ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    protein LLP homolog
    Names
    LLP homolog, long-term synaptic facilitation (Aplysia)

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001134464.2NP_001127936.1  protein LLP homolog

      See identical proteins and their annotated locations for NP_001127936.1

      Status: PROVISIONAL

      Source sequence(s)
      BC158738
      UniProtKB/TrEMBL
      B0BN98, F7FF98
      Conserved Domains (1) summary
      pfam10169
      Location:3117
      Laps; Learning-associated protein

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086025.1 Reference GRCr8

      Range
      57620925..57625924
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006241425.4XP_006241487.1  protein LLP homolog isoform X1

      See identical proteins and their annotated locations for XP_006241487.1

      UniProtKB/TrEMBL
      B0BN98, F7FF98
      Related
      ENSRNOP00000005794.4
      Conserved Domains (1) summary
      pfam10169
      Location:3117
      Laps; Learning-associated protein