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    Zfp507 zinc finger protein 507 [ Mus musculus (house mouse) ]

    Gene ID: 668501, updated on 30-Apr-2024

    Summary

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    Official Symbol
    Zfp507provided by MGI
    Official Full Name
    zinc finger protein 507provided by MGI
    Primary source
    MGI:MGI:1916378
    See related
    Ensembl:ENSMUSG00000044452 AllianceGenome:MGI:1916378
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm480; Znf507; mKIAA1084; 1810022O10Rik; A230056M16Rik
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription, DNA-templated. Predicted to be located in nucleus. Is expressed in early conceptus; inner cell mass; and oocyte. Orthologous to human ZNF507 (zinc finger protein 507). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in limb E14.5 (RPKM 7.0), CNS E11.5 (RPKM 6.6) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Zfp507 in Genome Data Viewer
    Location:
    7 B2; 7 21.37 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (35471768..35502749, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (35772343..35803000, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 42379 Neighboring gene dpy-19 like C-mannosyltransferase 3 Neighboring gene STARR-seq mESC enhancer starr_18641 Neighboring gene RIKEN cDNA E130304I02 gene Neighboring gene predicted gene, 36234 Neighboring gene predicted gene, 38990

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Transcriptome analysis of mouse stem cells and early embryos. Sharov AA, et al. PLoS Biol, 2003 Dec. PMID 14691545, Free PMC Article
    2. Isolation of novel tissue-specific genes from cDNA libraries representing the individual tissue constituents of the gastrulating mouse embryo. Harrison SM, et al. Development, 1995 Aug. PMID 7671812
    3. Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Okazaki N, et al. DNA Res, 2003 Aug 31. PMID 14621295
    4. Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. Guo G, et al. Dev Cell, 2010 Apr 20. PMID 20412781
    5. Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method. Piao Y, et al. Genome Res, 2001 Sep. PMID 11544199, Free PMC Article

    See all (22) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 507

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_177739.3 → NP_808407.2  zinc finger protein 507

      See identical proteins and their annotated locations for NP_808407.2

      Status: VALIDATED

      Source sequence(s)
      AC120378, AK129283, AK142141, BE994250
      Consensus CDS
      CCDS52204.1
      UniProtKB/Swiss-Prot
      Q3UQU3, Q6ZPY5, Q80VK1
      Related
      ENSMUSP00000058609.5, ENSMUST00000061586.11
      Conserved Domains (1) summary
      sd00017
      Location:632 → 652
      ZF_C2H2; C2H2 Zn finger [structural motif]

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      35471768..35502749 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030242902.2 → XP_030098762.1  zinc finger protein 507 isoform X1

      UniProtKB/Swiss-Prot
      Q3UQU3, Q6ZPY5, Q80VK1
      Conserved Domains (1) summary
      sd00017
      Location:632 → 652
      ZF_C2H2; C2H2 Zn finger [structural motif]

    2. XM_006540298.3 → XP_006540361.1  zinc finger protein 507 isoform X2

      Conserved Domains (2) summary
      smart00355
      Location:596 → 618
      ZnF_C2H2; zinc finger
      sd00017
      Location:570 → 590
      ZF_C2H2; C2H2 Zn finger [structural motif]
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6ZPY5.2 GenPept UniProtKB/Swiss-Prot:Q6ZPY5

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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