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    Zfp125 zinc finger protein 125 [ Mus musculus (house mouse) ]

    Gene ID: 22651, updated on 7-Sep-2023

    Summary

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    Official Symbol
    Zfp125provided by MGI
    Official Full Name
    zinc finger protein 125provided by MGI
    Primary source
    MGI:MGI:1336211
    See related
    AllianceGenome:MGI:1336211
    Gene type
    protein coding
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    ZT2
    Summary
    Enables DNA-binding transcription repressor activity and chromatin DNA binding activity. Acts upstream of or within cellular lipid metabolic process and negative regulation of transcription, DNA-templated. Is expressed in several structures, including brain; gut; heart; metanephros; and skeletal muscle. [provided by Alliance of Genome Resources, Apr 2022]
    Annotation information
    not in current annotation release
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    Genomic context

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    Location:
    12 8.28 cM

    Bibliography

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    Related articles in PubMed

    1. Isolation and characterization of the murine zinc finger coding gene, ZT2: expression in normal and transformed myogenic cells. Giorgi S, et al. Gene, 1999 Apr 1. PMID 10196477
    2. The Foxo1-Inducible Transcriptional Repressor Zfp125 Causes Hepatic Steatosis and Hypercholesterolemia. Fernandes GW, et al. Cell Rep, 2018 Jan 9. PMID 29320745, Free PMC Article
    3. Genetic dissection of the fatty liver QTL Fl1sa by using congenic mice and identification of candidate genes in the liver and epididymal fat. Suzuki M, et al. BMC Genet, 2016 Nov 17. PMID 27855657, Free PMC Article
    4. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518
    5. BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. Magdaleno S, et al. PLoS Biol, 2006 Apr. PMID 16602821, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription repressor activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables chromatin DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cellular lipid metabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within cellular lipid metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within cellular lipid metabolic process ISO
    Inferred from Sequence Orthology
    more info
    		 PubMed 
    acts_upstream_of_or_within lipid metabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within lipid metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within lipid metabolic process ISO
    Inferred from Sequence Orthology
    more info
    		 PubMed 
    acts_upstream_of_or_within negative regulation of DNA-templated transcription IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 125
    Nucleotide Protein
    Heading Accession and Version

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