Tas2r119 taste receptor, type 2, member 119 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Tas2r119provided by RGD
Official Full Name: taste receptor, type 2, member 119provided by RGD
Primary source: RGD:620733
See related: Ensembl:ENSRNOG00000011963 AllianceGenome:RGD:620733
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: T2R1; Tas2r1
Summary: Predicted to enable bitter taste receptor activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception of bitter taste. Predicted to be integral component of membrane. Orthologous to human TAS2R1 (taste 2 receptor member 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: 2q23

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	2	NC_086020.1 (84948489..84949496)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	2	NC_051337.1 (83237595..83238602)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	2	NC_005101.4 (85305225..85306232)

Chromosome 2 - NC_086020.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

T2R1, a receptor for bitter taste, is expressed in brainstem.
Title: Neuronal expression of bitter taste receptors and downstream signaling molecules in the rat brainstem.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables G protein-coupled receptor activity	IEA Inferred from Electronic Annotation more info
enables bitter taste receptor activity	IBA Inferred from Biological aspect of Ancestor more info
enables bitter taste receptor activity	IEA Inferred from Electronic Annotation more info
enables bitter taste receptor activity	ISO Inferred from Sequence Orthology more info
enables taste receptor activity	TAS Traceable Author Statement more info	PubMed

Process	Evidence Code	Pubs
involved_in G protein-coupled receptor signaling pathway	IEA Inferred from Electronic Annotation more info
involved_in biological_process	ND No biological Data available more info
involved_in detection of chemical stimulus involved in sensory perception of bitter taste	IBA Inferred from Biological aspect of Ancestor more info
involved_in detection of chemical stimulus involved in sensory perception of bitter taste	IEA Inferred from Electronic Annotation more info
involved_in detection of chemical stimulus involved in sensory perception of bitter taste	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
is_active_in membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: taste receptor type 2 member 119

Names: T2R119; T2R19; taste receptor type 2 member 1; taste receptor type 2 member 19

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_023993.1 → NP_076483.1 taste receptor type 2 member 119

See identical proteins and their annotated locations for NP_076483.1

Status: PROVISIONAL

Source sequence(s)

AF227140

UniProtKB/Swiss-Prot

Q9JKU1

UniProtKB/TrEMBL

A6JN06, F1LMS0

Related

ENSRNOP00000015904.1, ENSRNOT00000015904.3

Conserved Domains (1) summary

cd15016
Location:7 → 287

7tm_TAS2R1; mammalian taste receptor 2, subtype 1, member of the seven-transmembrane G protein-coupled receptor superfamily