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    Snrnp25 small nuclear ribonucleoprotein 25 (U11/U12) [ Mus musculus (house mouse) ]

    Gene ID: 78372, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Snrnp25provided by MGI
    Official Full Name
    small nuclear ribonucleoprotein 25 (U11/U12)provided by MGI
    Primary source
    MGI:MGI:1925622
    See related
    Ensembl:ENSMUSG00000040767 AllianceGenome:MGI:1925622
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    C16ORF33; 3300001G02Rik
    Summary
    Predicted to be involved in mRNA splicing, via spliceosome. Predicted to act upstream of or within RNA splicing and mRNA processing. Predicted to be located in cytosol; intercellular bridge; and nucleoplasm. Predicted to be part of U12-type spliceosomal complex. Is expressed in testis. Orthologous to human SNRNP25 (small nuclear ribonucleoprotein U11/U12 subunit 25). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in liver E14 (RPKM 36.3), liver E14.5 (RPKM 34.3) and 26 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Snrnp25 in Genome Data Viewer
    Location:
    11 A4; 11 18.82 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (32155415..32158996)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (32205415..32208996)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 40823 Neighboring gene predicted gene 12109 Neighboring gene interleukin 9 receptor Neighboring gene STARR-positive B cell enhancer ABC_E730 Neighboring gene STARR-positive B cell enhancer ABC_E11473 Neighboring gene rhomboid 5 homolog 1 Neighboring gene alpha-globin locus regulatory region Neighboring gene N-methylpurine-DNA glycosylase Neighboring gene nitrogen permease regulator-like 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Comparative genome analysis delimits a chromosomal domain and identifies key regulatory elements in the alpha globin cluster. Flint J, et al. Hum Mol Genet, 2001 Feb 15. PMID 11157800
    2. Minor spliceosome components are predominantly localized in the nucleus. Pessa HK, et al. Proc Natl Acad Sci U S A, 2008 Jun 24. PMID 18559850, Free PMC Article
    3. Altered expression of genes involved in regulation of vitamin A metabolism, solute transportation, and cytoskeletal function in the androgen-insensitive tfm mouse testis. O'Shaughnessy PJ, et al. Endocrinology, 2007 Jun. PMID 17332066
    4. Isolation of novel tissue-specific genes from cDNA libraries representing the individual tissue constituents of the gastrulating mouse embryo. Harrison SM, et al. Development, 1995 Aug. PMID 7671812
    5. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within RNA splicing IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    acts_upstream_of_or_within mRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in mRNA splicing, via spliceosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of U12-type spliceosomal complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of U12-type spliceosomal complex ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in intercellular bridge ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    part_of spliceosomal complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    U11/U12 small nuclear ribonucleoprotein 25 kDa protein
    Names
    U11/U12 snRNP 25 kDa protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_030093.3 → NP_084369.2  U11/U12 small nuclear ribonucleoprotein 25 kDa protein

      See identical proteins and their annotated locations for NP_084369.2

      Status: VALIDATED

      Source sequence(s)
      AA199179, AK019452, BC028766
      Consensus CDS
      CCDS24518.1
      UniProtKB/Swiss-Prot
      Q8VIK1, Q9CX75
      Related
      ENSMUSP00000046654.4, ENSMUST00000039601.10
      Conserved Domains (1) summary
      cd17058
      Location:31 → 119
      Ubl_SNRNP25; ubiquitin-like (Ubl) domain found in small nuclear ribonucleoprotein U11/U12 subunit 25 (SNRNP25) and similar proteins

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      32155415..32158996
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8VIK1.1 GenPept UniProtKB/Swiss-Prot:Q8VIK1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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