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    Ap5b1 adaptor-related protein complex 5, beta 1 subunit [ Mus musculus (house mouse) ]

    Gene ID: 381201, updated on 5-Mar-2024

    Summary

    Official Symbol
    Ap5b1provided by MGI
    Official Full Name
    adaptor-related protein complex 5, beta 1 subunitprovided by MGI
    Primary source
    MGI:MGI:2685808
    See related
    Ensembl:ENSMUSG00000049562 AllianceGenome:MGI:2685808
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm962; beta-5
    Summary
    Predicted to be involved in endosomal transport. Predicted to act upstream of or within protein transport. Predicted to be part of AP-type membrane coat adaptor complex. Orthologous to human AP5B1 (adaptor related protein complex 5 subunit beta 1). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Broad expression in duodenum adult (RPKM 13.9), small intestine adult (RPKM 11.8) and 24 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Ap5b1 in Genome Data Viewer
    Location:
    19 A; 19 4.34 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (5610278..5621290)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (5560250..5571262)

    Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene sorting nexin 32 Neighboring gene STARR-positive B cell enhancer ABC_E1208 Neighboring gene NSE3 homolog, SMC5-SMC6 complex component like Neighboring gene predicted gene, 31166 Neighboring gene ovo like zinc finger 1 Neighboring gene STARR-seq mESC enhancer starr_45393 Neighboring gene CapStarr-seq enhancer MGSCv37_chr19:5601776-5601959 Neighboring gene ribonuclease H2, subunit C Neighboring gene STARR-positive B cell enhancer ABC_E11011 Neighboring gene K(lysine) acetyltransferase 5

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    General gene information

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in endosomal transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in endosomal transport ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in vesicle-mediated transport NAS
    Non-traceable Author Statement
    more info
    PubMed 
    Component Evidence Code Pubs
    part_of AP-5 adaptor complex NAS
    Non-traceable Author Statement
    more info
    PubMed 
    part_of AP-type membrane coat adaptor complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of AP-type membrane coat adaptor complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in late endosome NAS
    Non-traceable Author Statement
    more info
    PubMed 

    General protein information

    Preferred Names
    AP-5 complex subunit beta-1
    Names
    adapter-related protein complex 5 beta subunit

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001033448.3NP_001028620.1  AP-5 complex subunit beta-1

      See identical proteins and their annotated locations for NP_001028620.1

      Status: VALIDATED

      Source sequence(s)
      AC126029
      Consensus CDS
      CCDS29470.1
      UniProtKB/Swiss-Prot
      Q3TAP4
      Related
      ENSMUSP00000094042.4, ENSMUST00000096318.4
    2. NM_001362046.1NP_001348975.1  AP-5 complex subunit beta-1

      Status: VALIDATED

      Source sequence(s)
      AC126029
      Consensus CDS
      CCDS29470.1
      UniProtKB/Swiss-Prot
      Q3TAP4
      Related
      ENSMUSP00000157737.2, ENSMUST00000235575.2

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000085.7 Reference GRCm39 C57BL/6J

      Range
      5610278..5621290
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006531784.2XP_006531847.1  AP-5 complex subunit beta-1 isoform X1

      See identical proteins and their annotated locations for XP_006531847.1

      UniProtKB/Swiss-Prot
      Q3TAP4